Defense logistics (DL) is an important and yet unexplored knowledge area of Production Engineering. Therefore, the purpose of this paper is to establish the DL problem domain. The focus is on industrial, technological, institutional, organizational and, specially, strategic management aspects applied to logistics in the defense sector. It also proposes a conceptual framework identifying DL objectives, functional areas and interfaces with the environment. The framework defines the Defense Logistics Base (DLB) as a system meant to create and sustain military capability, but also involved with the development of industrial capability, related to high and medium-high technologies, applied to high value products, with dual use. Furthermore, it suggests a research agenda for future work on strategic management related to DL.