2012
DOI: 10.1159/000343628
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Gowers’ Queen Square Case Notes on Chorea: A 21st Century Re-Appraisal

Abstract: Objective: To analyze the case notes of 127 patients with chorea admitted to the National Hospital at Queen Square, London, under the care of William Richard Gowers and review his contribution to the study of choreas. Methods: We consulted the case books available at the Queen Square Library, from 1878 to 1911, comprising 42 volumes. Results: 97 patients (76.3%) were female and the age of presentation ranged from 4 to 60 years (mean 14.3). 43 patients (33.8%) experienced recurrent attacks of chorea. 29 patient… Show more

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Cited by 8 publications
(5 citation statements)
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“…31 – 33 In his textbook, there is a lengthy description of chorea, in particular SC, based on his case notes of more than 120 children and young adults admitted to the National Hospital and many more in his outpatient clinic and private rooms. In a recent review of his 42 volumes of case notes from 1878 to 1911, 34 Gowers’ description of the phenomenology and natural history of chorea is in keeping with our current notions about the illness ( Figure 1 ). After having treated more than 120 children in hospital with SC, he clearly had an understanding of chorea as a syndrome distinct from other phenomena.…”
Section: Definition Of Chorea As a Syndromementioning
confidence: 77%
“…31 – 33 In his textbook, there is a lengthy description of chorea, in particular SC, based on his case notes of more than 120 children and young adults admitted to the National Hospital and many more in his outpatient clinic and private rooms. In a recent review of his 42 volumes of case notes from 1878 to 1911, 34 Gowers’ description of the phenomenology and natural history of chorea is in keeping with our current notions about the illness ( Figure 1 ). After having treated more than 120 children in hospital with SC, he clearly had an understanding of chorea as a syndrome distinct from other phenomena.…”
Section: Definition Of Chorea As a Syndromementioning
confidence: 77%
“…[31][32][33] In his textbook, there is a lengthy description of chorea, in particular SC, based on his case notes of more than 120 children and young adults admitted to the National Hospital and many more in his outpatient clinic and private rooms. In a recent review of his 42 volumes of case notes from 1878 to 1911, 34 Gowers' description of the phenomenology and natural history of chorea is in keeping with our current notions about the illness (Figure 1). After having treated more than 120 children in hospital with SC, he clearly had an understanding of chorea as a syndrome distinct from other phenomena.…”
Section: Definition Of Chorea As a Syndromementioning
confidence: 77%
“…His observations on this hyperkinetic disorder show that, unlike many of his contemporaries, he had a clear understanding of chorea as a syndrome distinct from other phenomena. Moreover, he was able to define that it could result from a myriad of conditions, such as rheumatic fever, stroke, Huntington's and Wilson's disease, among others 13 .…”
Section: Discussionmentioning
confidence: 99%