2024
DOI: 10.1101/2024.04.18.589619
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GPnotebook: A pan-cancer glycoproteomic database and toolkit for analysis of protein glycosylation changes associated with cancer phenotypes

Hui Zhang,
Yingwei Hu

Abstract: Protein glycosylation plays a pivotal role in various biological processes, and the analysis of intact glycopeptides (IGPs) has emerged as a powerful approach for characterizing alterations in protein glycosylation associated with diseases. Despite the critical insights gained from IGP analysis, there is an evident scarcity of intact glycopeptide database and specialized tools for a comprehensive glycoproteomic examination. In response to this deficiency, we have developed a Python package, "GPnotebook," which… Show more

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