“…The majority of trials assessing compression methods were conducted in a surgical setting: 14 were orthopaedic, 24,33,34,36,40,48,49,[51][52][53]59,60,63,64 16 general, 23,25,26,28,29,32,[37][38][39]41,42,44,50,54,61,62 six neurosurgical or after spinal surgery, 31,43,[55][56][57][58] three gynaecological 30,45,46 and one mixed surgical, 47 with only two trials 27,35 conducted among 257 medical patients at high risk of venous thromboembolism. After subdividing these trials into those assessing monotherapy and those assessing adjunctive therapy, the specific type of surgical or medical setting did not appear to influence the effectiveness of mechanical compression [heterogeneity 2 for monotherapy (on 5 df) = 4.6; p > 0.1, and heterogeneity 2 for adjunctive therapy (on 2 df) = 3.7; p > 0.1, not significant (NS); Figure 2].…”