1976
DOI: 10.1136/bmj.2.6042.969
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Graded compression for preventing deep venous thrombosis.

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Cited by 88 publications
(41 citation statements)
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“…The majority of trials assessing compression methods were conducted in a surgical setting: 14 were orthopaedic, 24,33,34,36,40,48,49,[51][52][53]59,60,63,64 16 general, 23,25,26,28,29,32,[37][38][39]41,42,44,50,54,61,62 six neurosurgical or after spinal surgery, 31,43,[55][56][57][58] three gynaecological 30,45,46 and one mixed surgical, 47 with only two trials 27,35 conducted among 257 medical patients at high risk of venous thromboembolism. After subdividing these trials into those assessing monotherapy and those assessing adjunctive therapy, the specific type of surgical or medical setting did not appear to influence the effectiveness of mechanical compression [heterogeneity 2 for monotherapy (on 5 df) = 4.6; p > 0.1, and heterogeneity 2 for adjunctive therapy (on 2 df) = 3.7; p > 0.1, not significant (NS); Figure 2].…”
Section: Description Of Trialsmentioning
confidence: 99%
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“…The majority of trials assessing compression methods were conducted in a surgical setting: 14 were orthopaedic, 24,33,34,36,40,48,49,[51][52][53]59,60,63,64 16 general, 23,25,26,28,29,32,[37][38][39]41,42,44,50,54,61,62 six neurosurgical or after spinal surgery, 31,43,[55][56][57][58] three gynaecological 30,45,46 and one mixed surgical, 47 with only two trials 27,35 conducted among 257 medical patients at high risk of venous thromboembolism. After subdividing these trials into those assessing monotherapy and those assessing adjunctive therapy, the specific type of surgical or medical setting did not appear to influence the effectiveness of mechanical compression [heterogeneity 2 for monotherapy (on 5 df) = 4.6; p > 0.1, and heterogeneity 2 for adjunctive therapy (on 2 df) = 3.7; p > 0.1, not significant (NS); Figure 2].…”
Section: Description Of Trialsmentioning
confidence: 99%
“…In nine trials [23][24][25][26][27][28][29][30][31] among 1292 patients assessing GCS as monotherapy, GCS produced a highly significant 66% (10) reduction in DVT [57/665 (8.6%) GCS vs 133/627 (21.2%) control, 2p < 0.00001; Figure 3a], with no evidence of heterogeneity of effect among the trials ( 2 on 8 df = 6.6; p = ns). Among these trials of GCS monotherapy, whilst six had assessed above-knee stockings [24][25][26][27]29,31 [odds reduction 68% (12)], only one had assessed below-knee stockings 28 [odds reduction 0% (60)], and in two trials the position of the stocking was unspecified 23,30 [odds reduction 69% (18); Figure 4].…”
Section: Graduated Compression Stockingsmentioning
confidence: 99%
“…A postal survey of orthopaedic surgeons in the UK showed that 68% used graded compression stockings as prophylaxis for DVT (Laverick, Croal and Mollan 1991). Their efficacy has been well documented in abdominal surgery (Holford 1976;Scurr et al 1977;Allan et al 1983;Turner, Cole and Brooks 1984;Wille-Jorgensen et al 1985;Jeffery and Nicolaides 1990), but there is little information on their use in orthopaedic surgery (Barnes et al 1978;Ishak and Morley 1981;Ohlund, Fransson and Starck 1983).…”
Section: Graded Compression Stockings For Prevention Of Deep-vein Thrmentioning
confidence: 99%
“…Stockings with graded compression extending from the ankle to the groin decrease the incidence of postoperative DVT (Holford 1976, Scum et al 1977, Barnes et a]. 1978, Tomgren 1980, Ishak and Morley 1981, Allan et al 1983, Nicolaides et al 1983, Bergqvist and Lindblad 1984.…”
Section: Discussionmentioning
confidence: 99%