Graft copolymers of carboxymethyl cellulose with N-vinylimidazole: synthesis and application for drug delivery

Chitosan Graft Copolymers with N-Vinylimidazole as Promising Matrices for Immobilization of Bromelain, Ficin, and Papain

“…To determine molecular weight of the grafted PVI chains, synthesized copolymers were subjected to oxidative degradation [ 22 ] followed by viscosimetry in ethanol at 20 °C of the isolated grafted chains. The molecular weights were calculated from the viscosity data processed by the Mark–Kuhn–Houwink–Sakurada equation [ 28 ]:…”

“…One of the promising methods for its modification is the graft copolymerization of chitosan with vinyl monomers [ 21 ]. For example, the N -vinylimidazole homopolymer, poly( N -vinylimidazole), PVI, is water-soluble and this will expand the range of solubility of the polysaccharide [ 22 ]. In addition, the high complexing properties of PVI to various compounds are well known [ 23 , 24 , 25 ], as well as the ability to form protein-like (co)polymers [ 26 ].…”

Synthesis, characterization and antimicrobial activity applications of grafted copolymer alginate-g-poly(N-vinyl imidazole)

“…20 N-Vinyl imidazole was graed onto different natural polymer to improve the antimicrobial activity such as chitosan, 21 carboxymethyl chitosan, 22 carboxymethyl starch of antibacterial activity against Xanthomonas perforans and Xanthomonas oryzae and carboxymethyl cellulose to be used as drug delivery system. 23,24 In the current work, we study the effect of different concentrations of N-vinyl imidazole and potassium persulfate (K 2 S 2 O 8 , KPS) onto the graing process onto sodium alginate. N-Vinyl imidazole graed onto sodium alginate was prepared, characterized via different techniques and the antibacterial activity effect of the synthesized materials was tested against different species of bacteria and fungus.…”

Synthesis of poly(styrene‐co‐allylamine)‐b‐poly(2‐(dimethylamino)ethyl methacrylate) graft copolymers via “grafting from” atom transfer radical polymerization and their self‐assembly in aqueous media

“…Among different copolymers, graft copolymers have been recently investigated as smart systems for application in different areas such as drug delivery, dye adsorption, and so forth 16–18 . Graft copolymerization starts with the preparation of a backbone polymer (macroinitiator) with a predetermined number of initiation sites that are used to initiate polymerization of the side chains 19,20 .…”

“…Among different copolymers, graft copolymers have been recently investigated as smart systems for application in different areas such as drug delivery, dye adsorption, and so forth. [16][17][18] Graft copolymerization starts with the preparation of a backbone polymer (macroinitiator) with a predetermined number of initiation sites that are used to initiate polymerization of the side chains. 19,20 Among different grafting strategies, "grafting from" strategy enables the preparation of long-grafts, and attached chains have narrow molecular weight distribution by using living polymerizations.…”