Nanocomposites of TiO2 co-doped with La and Zr were prepared using the microwave-assisted sol-gel method. The samples were characterized by X-ray diffraction (XRD), scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS), energy dispersive spectroscopy (EDS) and specific surface area measurement (BET). The XRD results revealed that all the catalysts showed an anatase phase. It was found that the particle size of La-Zr-TiO2 is much smaller than pure TiO2. Moreover, the denitrification efficiency of La-Zr-TiO2 was 65.77%, which was higher than that of the pure and mono-doped TiO2 in the experiment.