Granular cell ameloblastoma: A rare case report and review of literature

Kulkarni, Dinraj; Ingale, Yashwant; Ingale, Manjusha; Ajabrao, Bomble Nikhil; Mayank, Mrinal; Kulkarni, Apurva

doi:10.4103/ijdr.ijdr_407_17

Cited by 3 publications

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“…Sometimes, they extend to include tall columnar and cuboidal cells. [ 19 ] In our study, the typical reversal of polarity and subnuclear vacuolization was not observed in the tumour islands where granular cells have extended to embrace the peripheral tall columnar cells.…”

Section: Discussionmentioning

confidence: 39%

Revisiting Vickers and Gorlin criteria in histopathological subtypes of ameloblastoma

Adyanthaya,

Begum,

Devasia

et al. 2023

Journal of Oral and Maxillofacial Pathology

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Background: Ameloblastoma is a benign tumour of odontogenic epithelial origin arising from enamel organ tissue that has not undergone differentiation to the point of hard tissue formation. Aims: This study was conducted with an aim to provide a baseline data to analyse whether various histopathological variants of ameloblastoma satisfies all the characteristic histopathological features of Vickers and Gorlin criteria. Settings and Design: A retrospective study of 25 cases of intraosseous ameloblastoma was carried out in the Department of Oral Pathology and Microbiology in accordance with the Institutional Ethics Committee. Methods and Materials: Histopathological slides of ameloblastoma subtypes were analysed microscopically to assess Vickers and Gorlin criteria. Statistical Analysis Used: Statistical analysis was done using the Chi-square test. A P- value of < 0.05 was set for statistical significance. Results: Presence of hyperchromatic nuclei was seen in all the variants (100%), except for the desmoplastic variant which showed only 60% positivity. Basal cell palisading, reverse polarity and subnuclear vacuolization were seen predominantly only in acanthomatous (100%), and follicular variants (83%). Conclusions: Vickers and Gorlin criteria have become an integral part of diagnosis of histopathological subtypes of ameloblastoma and should be applied vigilantly in the diagnosis as these may not always fulfill all the gold standard criteria when individual subtypes are assessed.

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Section: Discussionmentioning

confidence: 39%

Revisiting Vickers and Gorlin criteria in histopathological subtypes of ameloblastoma

Adyanthaya,

Begum,

Devasia

et al. 2023

Journal of Oral and Maxillofacial Pathology

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“…[ 3 ] The current World Health Organization (WHO2017) classification of odontogenic tumors divides ameloblastoma into four types as follows: ameloblastoma, unicystic type, ameloblastoma extraosseous or peripheral type, and metastasizing malignant. [ 4 ] Ameloblastoma most significantly concerns oral pathologists due to its high incidence among all odontogenic tumors and true neoplastic (infiltrative and recurrent) potential combined with its varieties of histopathological patterns. [ 5 ] The six main histopathological subtypes (variants) of ameloblastoma are as follows: (a) follicular, (b) plexiform, (c) acanthomatous, (d) granular cells, (e) basal cell, and (f) desmoplastic form.…”

Section: Introductionmentioning

confidence: 99%

A case report on granular cell ameloblastoma – A rare histological entity

Mathew

2020

Indian J Radiol Imaging

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Granular cell ameloblastoma is a rare condition, accounting for 3.5% of all ameloblastoma cases that shows marked transformation in the cytoplasm of tumor cells, which are usually stellate reticulum-like cells. The transformed cells possess very coarse, granular eosinophilic cytoplasm. Granular cell ameloblastoma is aggressive in nature with a marked propensity for recurrence and can progress to metastasis. This article discusses a case report of a 35-year-old female patient diagnosed with granular cell ameloblastoma of the right mandible.

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Granular Cell Ameloblastoma: A Case Report of a Rare Histological Entity with the Review of Literature

Ashwinirani,

Das,

Pawar

2023

Medical Journal of Dr. D.Y. Patil Vidyapeeth

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Ameloblastoma is a benign odontogenic tumor accounting for 11% of all odontogenic tumors with various histological patterns. Granular cell ameloblastoma is a rare condition, accounting for 3.5% of all ameloblastoma cases. It is aggressive in nature with a marked propensity for recurrence and can progress to metastasis. This article reports a case of a 56-year-old female patient diagnosed with granular cell ameloblastoma of the right mandible.

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Granular cell ameloblastoma: A rare case report and review of literature

Cited by 3 publications

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Revisiting Vickers and Gorlin criteria in histopathological subtypes of ameloblastoma

Revisiting Vickers and Gorlin criteria in histopathological subtypes of ameloblastoma

A case report on granular cell ameloblastoma – A rare histological entity

Granular Cell Ameloblastoma: A Case Report of a Rare Histological Entity with the Review of Literature

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