Granular cell tumor of the appendix: a case report and literature review

Abstract

A granular cell tumor (GCT) is an unusual benign soft tissue tumor that can occur at any age and in any part of the body. GCTs are mostly found in the skin and subcutaneous tissues, bronchi, esophagus, breast tissue, and tongue. A GCT originating in the digestive tract, particularly in the appendix, is relatively rare and usually diagnosed as an incidental finding. We herein describe the first case of abdominal distension and occasional pain secondary to a GCT of the appendix in our hospital. The findings from this case suggest that a GCT of the appendix is a rare entity for which surgical resection is an efficient therapy.

Gastrointestinal Granular Cell Tumor: The First Report of a Multifocal and Potentially Hereditary Case

“…The gastrointestinal tract is involved in up to 11% of cases, with the esophagus, especially the distal esophagus, being the most frequently affected site, followed by the colon and the stomach [14]. There have also been reports of GCTs detected in the pancreas [15], biliary tree [16] or the appendix [17], but these locations are less common.…”