Granular cell tumour of the pectoral muscle mimicking breast cancer

Patel, Anish; Lefemine, Valentina; Yousuf, Syed Mansoor; Abou-Samra, Walid

doi:10.1186/1757-1626-1-142

Cited by 33 publications

(37 citation statements)

References 7 publications

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“…Aoyama et al (3), reported in their study of six cases of GCTs, a 54-year-old woman with a GCT in the left axillary cavity, which is very similar to our patient. Another patient with similar location of GCT in the upper outer quadrant of the right breast which appeared to be attached to the underlying pectoralis major muscle, was described by Patel et al (9). The mammographic appearence of the GCT was very similar to the patient from our case report.…”

Section: Discussionsupporting

confidence: 85%

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Granular cell tumor in axillary region: A rare entity

2018

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Abstract. A granular cell tumor (GCT), is a rare soft tissue tumor which may occur throughout the body, usually in the head and neck, skin or subcutaneous tissues of the trunk and upper extremities, and female genital region. A total of 5-8% of all cases of GCTs occur in the breast. GCT of the breast may mimic breast cancer both clinically and radiologically. GCTs are usually benign and solitary; however, approximately 2% occur as malignant tumors. Benign GCTs are treated with wide local excision and are associated with a good prognosis. The current case report presents findings in a patient with a benign form of GCT in a rare location, specifically in the axillary region.

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Section: Discussionsupporting

confidence: 85%

“…Microcalcifications are not normally a feature of GCTs. On ultrasound, GCTs can present as solid, poorly marginated lesions with marked posterior shadowing or as more benign-appearing well-circumscribed solid masses (8,9). MRI findings in a patient with GCT were described by Scaranelo et al (10).…”

Section: Discussionmentioning

confidence: 95%

Granular cell tumor in axillary region: A rare entity

2018

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“…Lymph node excision or sentinel lymph node biopsy is not indicated except malignant cases or colocalisation with malignancy. Although conservative approach has been suggested (Patel et al, 2008) it is not accepted. Extensive and/or combined treatment as for breast cancer should be avoided.…”

Section: Discussionmentioning

confidence: 99%

Granular Cell Tumour of the Breast Cancer: Challenging Clinical and Radiological Mimic of Cancer

Āboliņš¹,

Štrumfa²,

Vanags³

et al. 2012

Acta Chirurgica Latviensis

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SummaryGranular cell tumours (GCT) are rare soft tissue neoplasms of unclear histogenesis affecting almost any organ or tissues. Approximately 5% of GCT cases are located in the breast. Although granular cell tumour is benign in most instances, it can mimic breast cancer by radiological and clinical traits. Increased awareness of GCT is necessary to avoid misinterpretation as cancer and subsequent overtreatment

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“…GCT of the breast arises from intralobular breast stroma and occurs within the distribution of the cutaneous branches of the supraclavicular nerve [7,8]. It usually presents as a solitary non tender nodule but not uncommonly is multifocal and a manifestation of multicentric disease [7].The tumor is often found in the upper inner quadrant unlike breast cancer that is found in the upper outer quadrant [8,9].…”

Section: Review Of Literaturementioning

confidence: 99%

“…It usually presents as a solitary non tender nodule but not uncommonly is multifocal and a manifestation of multicentric disease [7].The tumor is often found in the upper inner quadrant unlike breast cancer that is found in the upper outer quadrant [8,9]. Since the tumor affects the innervation of the skin, contractions or shrinkage of the skin sometimes occur.…”

Section: Review Of Literaturementioning

confidence: 99%

Granular Cell Tumor of Breast: a Case Report and Review of Literature

Rexeena

Augustine

Nitish

et al. 2015

Indian J Surg Oncol

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This is an article reporting a case of granular cell tumor in the left breast in a 58 year old lady. Patient presented with a 3 × 3 cm mass in the left breast. Mammography reported a BIRADS 5 lesion in the left breast. With a clinical and radiological diagnosis of malignancy, patient was sent for FNAC (Fine needle aspiration Cytology). The cytology report was granular cell tumor. Following this patient underwent wide excision of the mass. Histopathology confirmed the cytological diagnosis of granular cell tumor of the breast. Patient is on regular follow up and is presently free of disease. The case report is followed up by a brief review of literature of granular cell tumor of the breast.Keywords Granular cell tumor . Breast . Excision Case ReportA 58 year old multiparous post menopausal lady presented with a history of lump in left breast since the past 3 months. Patient was initially evaluated in a local hospital. FNAC from the left breast lesion done outside was reported as lobular carcinoma of the breast. With this report patient was referred to our centre. On examination patient was ECOG 0. General and systemic examination of the patient was normal. On examination the left breast revealed a well defined firm lump measuring 3 × 3 cm in the upper inner quadrant without skin or chest wall fixity. No axillary or supraclavicular lymphadenopathy was present. Right breast and axilla were normal. Mammography revealed an irregular BIRADS 5 lesion in the left breast and normal right breast (Fig. 1). The patient underwent FNAC at our centre. The cytology smears showed clusters of cells with moderate to abundant granular eosinophilic cytoplasm and bland vesicular nucleus (Fig. 2) and the cytological diagnosis was granular cell tumor. As our pathologist is very experienced and in keeping with the local protocol we proceeded with a wide excision and frozen section on

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Granular cell tumour of the pectoral muscle mimicking breast cancer

Cited by 33 publications

References 7 publications

Granular cell tumor in axillary region: A rare entity

Granular cell tumor in axillary region: A rare entity

Granular Cell Tumour of the Breast Cancer: Challenging Clinical and Radiological Mimic of Cancer

Granular Cell Tumor of Breast: a Case Report and Review of Literature

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