Granular cell type of ameloblastoma

Jahanshahi, Gholamreza; Arzhang, Elham; Derisavy, Soheila; Davoodi, Laleh; Shakeri, Salman

doi:10.4103/1735-3327.231868

Cited by 3 publications

(2 citation statements)

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“…El oncocitoma de la mandíbula es muy raro y se dispone en filas o cordones y a veces en láminas. 13 Debido al escaso número de casos reportados de ameloblastoma, no existe un tratamiento específico. 2 La decisión debe considerar el patrón histológico, las encontraron nidos e islas con características ameloblásticas dentro del tejido capsular de tipo conectivo, fibroso y denso.…”

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Ameloblastoma uniquístico Ameloblastoma uniquístico de mandíbula

Soriano-Cueto

2023

Repert. Med. Cir.

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Introducción: los ameloblastomas son tumores epiteliales odontogénicos benignos, localmente invasivos que surgen de restos de la lámina dental y del epitelio odontogénico. Presentación del caso: paciente femenina de 39 años con aumento progresivo e indoloro en la región derecha de la cara y cuello. Se palpó tumoración bien circunscrita, indolora, de consistencia dura, no fluctuante de 5 cm de diámetro. La radiografía panorámica mostró una lesión radiolúcida unilocular cerca de la zona del primer molar izquierdo. La tomografía computarizada confirmó los hallazgos. La biopsia reveló una cavidad quística revestida por epitelio odontogénico fino. Se practicó resección total con mandibulectomía segmentaría. Discusión: el ameloblastoma es una lesión poco frecuente con características similares a los quistes maxilares. Los hallazgos histológicos e inmunohistoquímicos permiten diferenciarlo de otras lesiones benignas y malignas. Conclusión: es un tumor benigno de crecimiento lento y con alta capacidad de recidivas. La resección quirúrgica completa con bordes amplios es la medida terapéutica recomendada. El seguimiento a largo plazo es obligatorio debido al riesgo de recurrencia y transformación maligna.

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Section: I S C U S I ó Nunclassified

Ameloblastoma uniquístico Ameloblastoma uniquístico de mandíbula

Soriano-Cueto

2023

Repert. Med. Cir.

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“…Granular cell ameloblastoma is diagnosed by the presence of granular cells, which typically occur within the central area of the tumor and progressively replace the stellate reticulum [1]. It appears to be aggressive in nature, with an increased risk for recurrence and metastasis [2,[4][5][6]. The histological differential diagnosis of granular ameloblastoma includes granular cell odontogenic tumor, granular cell tumor, and congenital epulis.…”

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Granular cell ameloblastoma: A rare and unique variant

Saxena

Somanathan

Anitha

2022

Indian J Case Reports

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Ameloblastoma is a slow-growing and locally invasive epithelial odontogenic tumor of the jaw that runs a benign course in most cases. Granular cell ameloblastoma is a rare subtype of ameloblastoma, showing the granular transformation of its cytoplasm. It is considered as an aggressive variant of ameloblastoma. Herein, we report the case of a 34-year-old male patient who presented with a swelling in the left cheek for a 1-year duration with a recent rapid increase in size. Examination showed a 4 × 3 cm growth involving the left buccal mucosa and retromolar area. Imaging studies showed expansile lytic lesion mandible. Biopsy revealed neoplasm with odontogenic epithelial islands showing peripheral palisading of tall columnar cells with reversal of polarity and the center of the islands showing stellate reticulum-like cells which were markedly replaced by granular cells. Granular cells can appear in various odontogenic and non- odontogenic tumors. When there is extensive granular cell change in ameloblastoma, it should be differentiated from other oral lesions with granular cells including granular cell odontogenic tumor, granular cell tumor, and congenital epulis.Herein we report the case of a 34-year-old male patient presented with swelling left cheek of one-year duration with recent rapid increase in size. Examination showed a 4x3 cm growth involving left buccal mucosa and retromolar area. Imaging studies showed expansile lytic lesion mandible. Biopsy revealed neoplasm with odontogenic epithelial islands showing peripheral palisading of tall columnar cells with reversal of polarity and the center of the islands showing stellate reticulum like cells which were markedly replaced by granular cells. Granular cells can appear in various odontogenic and nonodontogenic tumors. When there is extensive granular cell change in ameloblastoma it should be differentiated from other oral lesions with granular cells including granular cell odontogenic tumour, granular cell tumour and congenital epulis.

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