Granulocytic sarcoma presenting as cauda equina syndrome

Isolated Recurrence of Intracranial Granulocytic Sarcoma Mimicking a Falx Meningioma in Acute Myeloblastic Leukemia

“…The term 'chloroma' has been derived from the Greek word chloros (green) because of the typical greenish appearance of the A B lesion. The green color of this tumor is originated from the high expression of myeloperoxidase, but it is not always expressed because it rapidly fades by exposure to oxygen 15) . It has been well known that granulocytic sarcoma occurs primarily in patients with AML, myeloproliferative and myelodysplastic syndrome 1,8,10) and, which has been almost always followed by bone marrow relapse after 1-19 months 12) .…”

Spinal Granulocytic Sarcoma Manifesting as Radiculopathy in a Nonleukemic Patient -Case Report-

“…2,[5][6][7][9][10][11][12]14,[16][17][18][19][20][21][22][23][24][25][26][27][28]30) The male predominance could be associated with the higher incidence of acute myeloid leukemia in men. 4) The affected sites included two cases at cervical, 17 at thoracic, 10 at lumbar, and three at sacral spinal levels.…”

“…Eight patients developed acute leukemia, 6,14,16,18,20,25,26,30) and six patients died following leukemic relapse or graft versus host disease. 6,14,16,18,20,26) On the other hand, 13 of the 26 patients showed no bone involvement, 2,[5][6][7]9,11,12,17,27,28) and only four patients died of chemotherapy or radiotherapy related clinical disorders. 6,7,17,24) This finding possibly reflects the aggressive initial treatment and prevention of progression to leukemia.…”

“…13) Granulocytic sarcoma most commonly occurs in the soft tissues of the head and neck, bone, and skin, 9) and less often in the central nervous system and spinal cord. 2,[5][6][7][9][10][11][12][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28]30) Granulocytic sarcoma seldom manifests before the identification of leukemia in the peripheral blood or bone marrow. 2,[5][6][7][9][10][11][12][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28]30) The finding of granulocytic sarcoma in p...…”

“…29) Spinal granulocytic sarcoma in aleukemic patients is rare but important because late bone marrow involvement may be related to blast crisis and cause death. 6,14,16,18,20,24,26) We treated a nonleukemic patient with radiculopathy caused by spinal extradural granulocytic sarcoma. This case indicates the importance of immunohistochemistry in the differential diagnosis, and the efficacy of positron emission tomography …”