Granuloma venereum

Abstract

Granuloma venereum is endemic in Zambia but there are no previous reports of the disease from this geographical area. Six cases of granuloma venereum in African females were discovered on biopsy specimens. One unusual case with primary cervical involvement simulating carcinoma of the cervix is presented. This case illustrates the difficulties of diagnosis and the ease with which it may be mistaken for malignancy in the absence of histological confirmation.

Donovanosis

“…However, carcinoma of the penis is also associated with low socioeconomic status, poor personal hygeine, promiscuity, and -c high rates of venereal disease (39, 125,127), factors common in patients with granuloma inguinale. In addition, some cases of alleged genital carcinoma coincident with or due to granuloma inguinale may actually represent the infection simulating a malignancy (120,128) Pseudoelephantiasis (11,55,75,129) ofthe genitals is another disfiguring complication ( Fig. 3).…”

Extragenital donovanosis: three cases from Western Australia.

“…9 Brigden and Guard alluded to three major extragenital manifestations in donovanosis: (1) blood borne dissemination to distant organs such as bones, joints, liver, spleen, and lungs; (2) contiguous spread from the genital region into adjacent pelvic organs; and (3) probable spread by autoinnoculation to remote skin sites as well as to the mucosal surfaces of the lips, gums, and pharynx.50…”