Granulomatous hepatitis due to Strongyloides stercoralis

Poltera, A. A.; Katsimbura, N.

doi:10.1002/path.1711130408

Cited by 37 publications

(10 citation statements)

References 17 publications

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“…In general, granulomatous hepatitis refers to an inflammatory liver disease associated with granuloma formation in the liver. Poltera et al reported that 3 out of 5 cases of granulomatous hepatitis due to S. stercoralis had cholestasis (11). Jaundice owing to reflex spasm of the sphincter of Oddi that is caused by S. stercoralis infection is rare, and it can also occur in Crohn's disease (12).…”

Section: Discussionmentioning

confidence: 99%

Strongyloides stercoralis Infection Causing Obstructive Jaundice and Refractory Pancreatitis: A Lesson Learned from a Case Study

et al. 2016

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A 58-year-old Japanese woman came to our institution because of leg edema and abdominal distention. She had developed acute pancreatitis 5 times in the past 3 years. Dilation of the bile duct and main pancreatic duct without obstruction was observed on computed tomography and magnetic resonance cholangiopancreatography. The presence of Strongyloides stercoralis was highly suspected from the biopsy sample from the duodenal papilla. Polymerase chain reaction amplification and sequencing of small subunit rDNA from paraffin-embedded specimens identified the worm as S. stercoralis. All of the symptoms were considered to be associated with S. stercoralis infection. Therefore, the patient was treated with oral administration of ivermectin. Subsequently, symptoms and laboratory data improved. There has been no recurrence of the symptoms to date.

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Section: Discussionmentioning

confidence: 99%

Strongyloides stercoralis Infection Causing Obstructive Jaundice and Refractory Pancreatitis: A Lesson Learned from a Case Study

et al. 2016

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“…In visceral larva migrans due to Toxocara canis or T. cati, there are a massive outpouring of eosinophils and often areas of central necrosis (10). Hepatic granulomas due to Strongyloides stercoralis and Enterobius vermicularis were also reported (11,12). The absence of eggs or massive outpouring of eosinophils in this case contributed to rule out the other helminths as well as the morphologic features of a nematode.…”

Section: Discussionmentioning

confidence: 66%

“…Out of helminths, other species may infest the liver to form a hepatic nodule, in which the possibilities of Enterobius vermicularis, Ascaris lumbricoides, Strongyloides stercoralis, Toxocara canis, Capillaria hepatica, Clonorchis sinensis, and Fasciola hepatica should be considered (10)(11)(12). The eggs are usually found in the granulomatous lesion in the cases of the schistosomiasis, hepatic capillariasis, fascioliasis, paragonimiasis, and ascariasis.…”

Section: Discussionmentioning

confidence: 99%

The First Human Case of Hepatic Dirofilariasis

Kim

Yeom

et al. 2002

J Korean Med Sci

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Most of human dirofilariasis are pulmonary or subcutaneous infections, but there have been a few reports of human dirofilariasis in unusual sites, such as large vessels, mesentery, peritoneal cavity, and spermatic cord. We present the first case of human hepatic dirofilariasis, which was surgically diagnosed. A 39-year-old man without any evidence of systemic symptom was found incidentally to have a hepatic nodule during routine physical check-up. The histologic findings of the resected lesion showed a granulomatous lesion with central necrosis containing up to 35 transverse sections of a nematode, ranging 30-80 micro m in diameter. Thin (1.5-5 micro m) cuticle with transverse striations surrounded polymyarian and muscle bundles occupied a sixth of both sides of outer body cavity. Central portion of the body cavity was occupied with an intestine-like tubular structure and a larger reproductive tube. These microscopic findings were consistent with degenerated Dirofilaria immitis. Antibody test by enzyme-linked immunosorbent assay for patient serum reacted positively against adult D. immitis antigen.

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“…Granulomatöse Entzündungen in verschiedenen Organen, wie z. B. der Leber, werden sporadisch diagnostiziert [7]. Bakterielle oder mykotische Superinfektionen sind die Folge der Hyperinfektion, die in Septikämie, Pneumonie, Meningitis oder Ileus oft einen fulminanten letalen (87%) Ausgang haben [3,4,13,14].…”

Section: Klinische Verlaufsformenunclassified

Schwere Durchf�lle bei niedrig malignem B-Zell-Lymphom

et al. 2004

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A 52-year old female presented with a low, malignant centroblastic-centrocytic lymphoma. After splenectomy and under steroid therapy it came to the eruption of a latent Strongyloides stercoralis infection, which the patient had presumably been suffering from for several years. Due to the immunodeficient condition and under continued steroid therapy even three courses of high dose anthelmintic therapy could not eradicate the parasites. The patient died of fulminant sepsis.

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Granulomatous hepatitis due to Strongyloides stercoralis

Cited by 37 publications

References 17 publications

<i>Strongyloides stercoralis</i> Infection Causing Obstructive Jaundice and Refractory Pancreatitis: A Lesson Learned from a Case Study

<i>Strongyloides stercoralis</i> Infection Causing Obstructive Jaundice and Refractory Pancreatitis: A Lesson Learned from a Case Study

The First Human Case of Hepatic Dirofilariasis

Schwere Durchf�lle bei niedrig malignem B-Zell-Lymphom

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