Granulomatous pneumonia due to pythiosis in captive South American coatis (Nasua nasua)

Bezerra, Kalinne Stephanie; Santos, Tarcísio Ávila dos; Rosa, Janaina Marcela Assunção; Pescador, Carolina Argenta; Dutra, Valéria; Nakazato, Luciano; Driemeier, David; Colodel, Edson M.

doi:10.1590/1678-5150-pvb-6459

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…Granulomatous pneumonia caused by oomycetes may also be considered as a differential diagnosis given the histologic identification of non-staining hyphae. However, there are only rare reports of a primary pulmonary presentation of pythiosis (one jaguar and two South American coatis) ( 12 , 13 ) and of dissemination of lagenidiosis to the lung (two dogs) ( 14 ) in veterinary literature. Another differential for large pulmonary masses in any species is primary pulmonary neoplasia.…”

Section: Discussionmentioning

confidence: 99%

Case Report: Pulmonary Conidiobolomycosis in a Vietnamese Pot-Bellied Pig

et al. 2021

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An adult castrated male Vietnamese pot-bellied pig had a 1-week history of acute dyspnea and lethargy. Minimal diagnostic testing was authorized by the owner, resulting in treatment with a third-generation cephalosporin and a non-steroidal anti-inflammatory drug. Partial improvement was observed after a week; however, the pig died 2 weeks after the initial onset of clinical signs. Macroscopically, ~90% of the left lung was effaced by large masses with a caseonecrotic center. Histologic examination revealed eosinophilic granulomas with myriad, intralesional, negatively staining hyphae highlighted by “sleeves” of hypereosinophilic material (Splendore-Hoeppli material). Infection with an oomycete or “zygomycete” (i.e., organisms of the order Entomophthorales or Mucorales) was initially considered. Pan-fungal PCR and sequencing performed on formalin-fixed, paraffin-embedded lung tissue identified Conidiobolus spp., consistent with a diagnosis of primary pulmonary conidiobolomycosis. There are only a few reports of infections with Conidiobolus spp. (and other members of the order Entomophthorales) in swine. Unlike humans and other animal species, conidiobolomycosis in pigs presents more commonly as a primary pulmonary disease rather than rhinofacial or nasopharyngeal disease.

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Section: Discussionmentioning

confidence: 99%

Case Report: Pulmonary Conidiobolomycosis in a Vietnamese Pot-Bellied Pig

et al. 2021

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Esophageal and gastric pythiosis in a dog

Silva,

Martins,

Pereira

et al. 2024

Cienc. Rural

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Pythiosis is the disease caused by aquatic oomycetes of the genus Pythium. In dogs the typical course of the disease involves the gastrointestinal tract, characterized by transmural thickening of the stomach or intestines. However, infection by Pythium spp. has only rarely been recognized as a cause of esophagitis in dogs. Thus, the present reports a case of esophageal and gastric pythiosis in an eight-month-old female pit bull dog. The dog was attended at the hospital after two months presenting regurgitation and dyspnea. It was reported that the dog lived in an urban area and had no previous sanitary issues. At clinical examination it was noted that the dog presented crackling sounds at pulmonary auscultation. A support therapy accompanied by antibiotics has been employed; however, 22 days after hospitalization the clinical condition worsened, and the dog died. At necropsy, the wall of the distal segment of the esophagus and the cardia and part of the fundus of the stomach were expanded by a focal extensive irregular intramural annular mass. Additionally, there was a transmural esophageal fistula. At histology, the walls of the esophagus and stomach were extensively expanded by multifocal extensive areas of necrosis, associated with a pyogranulomatous infiltrate and abundant granulation tissue containing multiple negative images of hyphae that were highlighted by silver impregnation (Grocott). Furthermore, immunohistochemistry and PCR for P. insidiosum were both positive in samples of paraffin-embedded esophageal tissue.

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Cutaneous pythiosis in equines in the Amazon Biome

et al. 2023

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The study aimed to describe the clinicopathological aspects of 37 cases of pythiosis, 34 in horses and three in mules, from properties located in the Amazon biome of Pará, Brazil. The clinical signs observed in the animals were weakness, poor-to-regular nutritional status, pale mucous membranes, itching at the lesion site, and lameness when the limbs were affected. The lesions were located on the lips, nostrils, rib region, thoracic and abdominal walls, scapular, distal limbs, foreskin, perineum and udder. Macroscopically, ulcerative and granulation-tissue-like masses were observed, with fistulous tracts filled with yellowish and foul-smelling serosanguinous discharges. In the biopsy, it was possible to visualize white and firm areas with foci of yellowish necrotic material and hardened masses, called kunkers. The histopathological examination showed a pyogranulomatous inflammatory reaction with the presence of Pythium insidiosum hyphae, which were impregnated with black, confirming the diagnosis of pythiosis in equids in the Amazon biome, being the first report of the disease in mules in the region.

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Granulomatous pneumonia due to pythiosis in captive South American coatis (Nasua nasua)

Cited by 3 publications

References 16 publications

Case Report: Pulmonary Conidiobolomycosis in a Vietnamese Pot-Bellied Pig

Case Report: Pulmonary Conidiobolomycosis in a Vietnamese Pot-Bellied Pig

Esophageal and gastric pythiosis in a dog

Cutaneous pythiosis in equines in the Amazon Biome

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