Granulomatous pyoderma gangrenosum of the genitalia in the absence of Crohn′s disease

Abstract

Pyoderma gangrenosum (PG) is a rare ulcerative neutrophilic disorder of the skin. Atypical variants of PG such as vegetative PG, bullous PG, and pustular forms are described in literature. Occasionally, granulomatous reaction in dermis may be seen on histology when PG is associated with Crohn's disease or in the vegetative variant of PG. We report a case of granulomatous PG involving the genitalia in a 43-year-old female without associated inflammatory bowel disease.

Pyoderma gangrenosum

“…Few cases of isolated genital PG have been reported with only 4 from India. [ 4 5 6 7 ] Our patient responded well to a combination of therapy with dapsone, colchicine, and oral prednisolone in addition to local wound care. This case is presented to highlight the importance of keeping PG as a differential diagnosis of penile ulcers refractory to usual treatment modalities.…”