Granulosa Cell Tumour of the Ovary

Abstract

Granulosa cell tumour of the ovary is rare neoplasm. They belong to the group of ovarian sex-cord stromal tumour. It represents less than 2% of all ovarian tumour, but account for 6% of all ovarian malignancy. (1) The prognosis of Juvenile Granulosa cell tumours is excellent tumour recurrence and metastasis is rare, where as Adult are low-grade indolent malignant neoplasm, that display a significant propensity for recurrence and metastasis and can complicate management. KEY WORDS: Granulosa cell tumour, sex-cord tumour, Call-Exner bodies INTRODUCTION:The spectrum of ovarian neoplasm covers an extremely wide range of tumours. The best recognised of these are epithelial cell tumour , and Granulosa cell tumour is the less common variant and it accounts for 70% of all sex-cord tumour. (2 ) Based on histopathology findings two histological types of granulosa cell tumours can be distinguished Juvenile and Adult type. The adult type of granulosa cell tumour is more common (95%) then the juvenile type and usually causes symptoms that are related to excessive estrogen production, such as vaginal bleeding, endometrial hyperplasia and carcinoma. Here we report a case of huge granulosa cell tumour of ovary in a postmenopausal woman.