As a beneficial supplement to centralized power generation(PG), distributed PG has attracted more and more attention in the world because of its many advantages, such as safety and reliability, low pollution, energy saving and economy, flexible installation location and so on. At present, many scholars at home and abroad have analyzed and studied the power flow algorithm of distribution network with distributed generation(DG) from different angles, and have made some achievements. In this paper, Three phase power flow calculation(TPPFC) of weak loop distribution network(LDN) with multiple distributed generators is analyzed and studied. The influence of human DG on power flow of distribution network and the modeling of various DG and load are analyzed; The three-phase power flow(TPPF) algorithm is discussed. Finally, through the simulation experiment of the TPPFC of the weak LDN with multiple distributed generators, the application of distributed generators to the distribution system(DS) is discussed. The simulation calculation of the IEEE-14 node DS and the ieee-33 node DS with distributed generators is accurate and fast.