Graphdiyne nanosheet as a novel sensing platform for self-enhanced electrochemiluminescence of MOF enriched ruthenium (II) in the presence of dual co-reactants for detection of tumor marker

Bahari, Delnia; Babamiri, Bahareh; Moradi, Kayvan; Salimi, Azam; Hallaj, Rahman

doi:10.1016/j.bios.2021.113657

Cited by 49 publications

(24 citation statements)

References 34 publications

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“…In addition, due to the protection of antibody activity by NKF, the storage time of the sensor was prolonged, thereby improving its stability. Combined with the related references and experimental results, − we inferred that NKF improved the sensitivity and storage stability of the biosensor through a targeted antibody immobilization strategy.…”

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confidence: 54%

Highly Efficient PTCA/Co₃O₄/CuO/S₂O₈^2– Ternary Electrochemiluminescence System Combined with a Portable Chip for Bioanalysis

et al. 2022

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Herein, we reported an efficient electrochemiluminescence (ECL) biosensor chip for sensitive detection of neuron-specific enolase (NSE). First, 3,4,9,10-perylenetetracarboxylic acid with good luminescence characteristics was used as a luminophore to obtain a stable ECL signal. Subsequently, hollow porous Co3O4/CuO concave polyhedron nanocages (CPNCs) were designed as co-reaction promoters to amplify the luminescence signals for highly sensitive trace detection of NSE. In brief, the rapid cyclic conversion of Co3+/Co2+ and Cu2+/Cu+ redox pairs could continuously catalyze the reduction of persulfate (S2O8 2–), thus providing a large number of essential active intermediates (SO4 •–) for ECL emission. Meanwhile, the unique structure of Co3O4/CuO CPNCs possessed a large specific surface area, which greatly improved its catalytic efficiency. Third, NKFRGKYKC was developed as an affinity ligand for specific antibody fixation, which improved incubation efficiency and protected bioactivity of antibodies. Finally, we independently designed a microchip and applied it for ECL detection to improve the practical application ability of the sensor. The developed biosensor exhibited good sensitivity with a wide linear range (10 fg/mL to 100 ng/mL) and a low detection limit (3.42 fg/mL), which played an active role in the clinical application of sensing analysis.

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confidence: 54%

Highly Efficient PTCA/Co₃O₄/CuO/S₂O₈^2– Ternary Electrochemiluminescence System Combined with a Portable Chip for Bioanalysis

et al. 2022

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“…1 In particular, pancreatic cancer is a common malignant tumor with a high degree of malignancy. 2,3 Therefore, the ultrasensitive detection of CA19-9, a specific marker of pancreatic cancer, is an effective means to achieve an early diagnosis and significantly improve the cure rate. 4 CdLa 2 S 4 has found specific applications in the fields of environmental purification, photocatalytic hydrogen production, 5,6 and energy storage and conversion.…”

Section: Introductionmentioning

confidence: 99%

Novel Photoelectrochemical Biosensing Platform Based on a Double Type II CdLa₂S₄/SnIn₄S₈/Sb₂S₃ Ternary Heterojunction as Photoactive Materials and NiCo₂O₄ Nanospheres as a Photoquencher for CA19-9 Detection

et al. 2022

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A novel signal-off biosensing platform based on the CdLa2S4/SnIn4S8/Sb2S3 heterojunction as photoactive materials and NiCo2O4 nanospheres as a photoquencher was developed to achieve the sensitive detection of CA19-9. First, the narrow band gap hydrangea-like CdLa2S4/SnIn4S8/Sb2S3 not only provided excellent photocurrent response but also supplied a mass of active sites that facilitated the loading of capture antibody (Ab1). Second, a double type II CdLa2S4/SnIn4S8/Sb2S3 heterojunction promoted the fast separation and migration of photogenerated e–/h+ and overcame the problem of short carrier lifetime caused by the recombination of photogenerated carriers. In addition, to improve the sensitivity of the constructed sensor to detect CA19-9, signal tags (p-type NiCo2O4) with large steric hindrance were introduced to accomplish signal amplification by the effect of double signal quenching. On one hand, NiCo2O4, which was strongly responsive to visible light, utilized its own advantages to compete for AA with CdLa2S4/SnIn4S8/Sb2S3, resulting in a decrease in the hole scavenging rate of the substrate. On the other hand, the photoquencher NiCo2O4 also prevented AA from contacting the matrix and further aggravated the photoelectrochemical (PEC) signal-damping effect. The PEC immunosensor was prepared with brilliant selectivity and splendid stability to detect CA19-9 (0.001–50 U/mL), and the detection limit was 0.0004 U/mL (S/N = 3).

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“…Due to the unique properties of the GDY materials and their composites (e.g., high electrical conductivities, large specific surface areas, unique and uniformly distributed pores, strong interactions toward the analytes, promoted ion adsorption/diffusion), [75,125,209] they are conducive to the pre-enrichment of detected substances in the electrochemical detection processes. [210,211] Therefore, the GDY materials and their composites have been employed to monitor various analytes, such as environmental pollutants [34,212,213] and biomolecules. [214][215][216][217][218] A series of GDY materials and their composites, including GDY, GDY oxides (GDYO), and reduced GDYO materials have been synthesized by means of chemical (cr-GDYO) and electrochemical approaches (er-GDYO).…”

Section: Electrochemical Sensingmentioning

confidence: 99%

Graphdiyne Electrochemistry: Progress and Perspectives

Chen

Jiang

Yang

2022

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Graphdiyne, a carbon allotrope, was synthesized in 2010 for the first time. It consists of two acetylene bonds between adjacent benzene rings. Graphdiyne and its composites thus exhibit ultrahigh intrinsic electrochemical activities. As “star” electrode materials, they have been utilized for various electrochemical applications. With the aim of giving a full screen of graphdiyne electrochemistry, this review starts from the history of graphdiyne materials, followed by their structural and electrochemical features. Recent progress and achievements in the synthesis of graphdiyne materials and their composites are overviewed. Subsequently, various electrochemical applications of graphdiyne materials and their composites are summarized, covering those in the fields of electrochemical energy conversion, electrochemical energy storage, and electrochemical sensing. The perspectives of graphdiyne electrochemistry are also discussed and outlined.

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Graphdiyne nanosheet as a novel sensing platform for self-enhanced electrochemiluminescence of MOF enriched ruthenium (II) in the presence of dual co-reactants for detection of tumor marker

Cited by 49 publications

References 34 publications

Highly Efficient PTCA/Co₃O₄/CuO/S₂O₈^2– Ternary Electrochemiluminescence System Combined with a Portable Chip for Bioanalysis

Highly Efficient PTCA/Co₃O₄/CuO/S₂O₈^2– Ternary Electrochemiluminescence System Combined with a Portable Chip for Bioanalysis

Novel Photoelectrochemical Biosensing Platform Based on a Double Type II CdLa₂S₄/SnIn₄S₈/Sb₂S₃ Ternary Heterojunction as Photoactive Materials and NiCo₂O₄ Nanospheres as a Photoquencher for CA19-9 Detection

Graphdiyne Electrochemistry: Progress and Perspectives

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Graphdiyne nanosheet as a novel sensing platform for self-enhanced electrochemiluminescence of MOF enriched ruthenium (II) in the presence of dual co-reactants for detection of tumor marker

Cited by 49 publications

References 34 publications

Highly Efficient PTCA/Co3O4/CuO/S2O82– Ternary Electrochemiluminescence System Combined with a Portable Chip for Bioanalysis

Highly Efficient PTCA/Co3O4/CuO/S2O82– Ternary Electrochemiluminescence System Combined with a Portable Chip for Bioanalysis

Novel Photoelectrochemical Biosensing Platform Based on a Double Type II CdLa2S4/SnIn4S8/Sb2S3 Ternary Heterojunction as Photoactive Materials and NiCo2O4 Nanospheres as a Photoquencher for CA19-9 Detection

Graphdiyne Electrochemistry: Progress and Perspectives

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Highly Efficient PTCA/Co₃O₄/CuO/S₂O₈^2– Ternary Electrochemiluminescence System Combined with a Portable Chip for Bioanalysis

Highly Efficient PTCA/Co₃O₄/CuO/S₂O₈^2– Ternary Electrochemiluminescence System Combined with a Portable Chip for Bioanalysis

Novel Photoelectrochemical Biosensing Platform Based on a Double Type II CdLa₂S₄/SnIn₄S₈/Sb₂S₃ Ternary Heterojunction as Photoactive Materials and NiCo₂O₄ Nanospheres as a Photoquencher for CA19-9 Detection