This review summarizes the most recent studies on synaesthesia, particularly studies on grapheme-colour synaesthesia, time-space synaesthesia, and coloured-hearing synaesthesia. Based on behavioural as well as neuroimaging studies, there is emerging evidence that synaesthesia is not only caused by the cross activation of two sensory areas but that it may require additional binding processes, which are assumed to take place in the parietal lobe. However, divergent results exist with respect to the lateralization of this effect, i.e. whether it is the left or right parietal lobe most responsible. Studies also indicate that attention modulates the synaesthetic experience. Furthermore, it has been shown that synaesthetes demonstrate a higher level of connectivity, thus supporting the view of a genetic pre-disposition of synaesthesia.
What is synaesthesia?Synaesthesia describes a rare condition in which a particular sensory stimulus involuntarily evokes an additional, concurrent sensation, which may or may not be in the same sensory modality. The term "synaesthesia" is a combination of the Greek words σύν (syn) = together/ joined, and of the Greek word αἲσθησις (aisthēsis), which means perceptions.In other words, a synaesthete perceives two joint and concurrent perceptions, where only one is caused by a real, external stimulus, while the other is an internally-evoked synaesthetic experience without any direct external cause.The cross-link between the real stimulus and the synaesthetic experience is always the same, for example: seeing the letter A always evokes the synaesthetic experience of seeing the letter in yellow, independent of the real printed colour. In order to understand the processes behind synaesthesia, one has to bear in mind that perception goes beyond the simple processing of sensory information. In general, other cognitive processes involving experience and expectancy, and additionally, conflicting and interfering information, always influence perception. This is the same for synaesthetes and non-synaesthetes. However, the important difference between synaesthesia and, for example, a learned association is that a synaesthetic experience cannot be trained and thus the concurrent synaesthetic experience is involuntary and automatically generated. This cross-sensational perception is highly consistent throughout the lifespan, as it remains unchanged from early childhood.It is also important to note that synaesthesia is by no means a psychological, psychiatric,