Graphene-Based Materials: Biological and Biomedical Applications

Papi, Massimiliano

doi:10.3390/ijms22020672

Cited by 12 publications

(4 citation statements)

References 11 publications

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“…Beneficial properties of GBMs include supplying electrical conductivity, which enhances mechanical strength and cellular behavior. The GBMs incorporation has been shown to improve the mechanical properties of bio-composites; higher concentrations of GBMs result in more suitable mechanical properties, which are adjustable by concentration for the target tissue [ 39 , 40 , 41 ]. In addition, the hydrophobicity of NTE structures enhances with increasing G amounts, which affects nerve cell attachment, proliferation, and differentiation.…”

Section: Tissue-engineered Scaffolds With Gbm and Neural Tissuesmentioning

confidence: 99%

Graphene-Based Materials Prove to Be a Promising Candidate for Nerve Regeneration Following Peripheral Nerve Injury

et al. 2021

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Peripheral nerve injury is a common medical condition that has a great impact on patient quality of life. Currently, surgical management is considered to be a gold standard first-line treatment; however, is often not successful and requires further surgical procedures. Commercially available FDA- and CE- approved decellularized nerve conduits offer considerable benefits to patients suffering from a completely transected nerve but they fail to support neural regeneration in gaps >30 mm. To address this unmet clinical need, current research is focused on biomaterial-based therapies to regenerate dysfunctional neural tissues, specifically damaged peripheral nerve, and spinal cord. Recently, attention has been paid to the capability of graphene-based materials (GBMs) to develop bifunctional scaffolds for promoting nerve regeneration, often via supporting enhanced neural differentiation. The unique features of GBMs have been applied to fabricate an electroactive conductive surface in order to direct stem cells and improve neural proliferation and differentiation. The use of GBMs for nerve tissue engineering (NTE) is considered an emerging technology bringing hope to peripheral nerve injury repair, with some products already in preclinical stages. This review assesses the last six years of research in the field of GBMs application in NTE, focusing on the fabrication and effects of GBMs for neurogenesis in various scaffold forms, including electrospun fibres, films, hydrogels, foams, 3D printing, and bioprinting.

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Section: Tissue-engineered Scaffolds With Gbm and Neural Tissuesmentioning

confidence: 99%

Graphene-Based Materials Prove to Be a Promising Candidate for Nerve Regeneration Following Peripheral Nerve Injury

et al. 2021

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“…Frontiers in Carbon frontiersin.org electronic, mechanical, and optical properties which have made them adaptable in several fields of scientific innovations (Sang et al, 2019;Adeola and Forbes, 2021a). Graphene (2D nanocarbon) and its derivatives can be functionalized for use in a wide range of fields, including environmental remediation, medicine, and electronics (Khenfouch et al, 2016;Liu et al, 2020;Papi, 2021;Hashmi et al, 2022). Figure 9 reflects the most common types/forms of graphenic materials, they are graphite, CNTs, reduced graphene oxide, and fullerenes, among others.…”

Section: Figurementioning

confidence: 99%

Microwave-assisted synthesis of carbon-based nanomaterials from biobased resources for water treatment applications: emerging trends and prospects

2023

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Carbon-based nanomaterials have drawn significant interest as desirable nanomaterials and composites for the adsorptive removal of various classes of pollutants from water owing to their versatile physicochemical properties. The underlying sorption mechanisms serve as the bedrock for the development of carbonaceous adsorbents for various target pollutants. Microwave-assisted synthesis can be regarded as a recent and well-advanced technique for the development of carbon-based nanomaterials, and the use of biobased materials/wastes/residues conforms with the concept of green and sustainable chemistry. For advancements in carbon-based functional nanomaterials and their industrial/field applications, it is essential to fully comprehend the sorption performance and the selective/non-selective interaction processes between the contaminants and sorbents. In this regard, research on the development of carbon-based nanomaterials for the adsorption of chemical contaminants, both organic and inorganic, in water has made considerable strides as discussed in this review. However, there are still several fundamental hurdles associated with microwave-assisted chemical synthesis and commercial/industrial scale-up applications in nano-remediation. The challenges, benefits, and prospects for further research and development of carbon-based nanomaterials/nanocomposites for the purification of water are also discussed.

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“… 8 At present, it is used in tissue regeneration and biomedical fields: tendon regeneration, nerve regeneration, skin regeneration, biosensing and medical detection, medical diagnosis, and disease indicators. 9 , 10 , 11 , 12 To explore the potential of graphene-based materials for biomedical applications, researchers need to explore different approaches to their synthesis, characterization, and application. Although graphene-based materials have many advantages, they still need to be adjusted in specific use scenarios using technical means such as 2D materials engineering to further improve their applicability.…”

Section: Introductionmentioning

confidence: 99%

Advances in graphene-based 2D materials for tendon, nerve, bone/cartilage regeneration and biomedicine

Gao,

Wang,

Fan

2024

iScience

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Graphene-Based Materials: Biological and Biomedical Applications

Abstract: This editorial aims to summarize the eleven scientific papers published in the Special Issue “Graphene-Based Materials: Biological and Biomedical Applications” [...]

Cited by 12 publications

References 11 publications

Graphene-Based Materials Prove to Be a Promising Candidate for Nerve Regeneration Following Peripheral Nerve Injury

Graphene-Based Materials Prove to Be a Promising Candidate for Nerve Regeneration Following Peripheral Nerve Injury

Microwave-assisted synthesis of carbon-based nanomaterials from biobased resources for water treatment applications: emerging trends and prospects

Advances in graphene-based 2D materials for tendon, nerve, bone/cartilage regeneration and biomedicine

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