This study aims to design a metamaterial sensor to detect glucose levels in the human body so that the severity of diabetic patients can be determined.The biomolecules are placed over gold metamaterial to observe the behavior of the sensor. The proposed model is analyzed for both phases of GST (amorphous GST [aGST] phase and crystalline GST [cGST] phase). The design is analyzed for parameters like absorption, angle of incidence of light, the concentration of glucose biomolecules, substrate, tuning of the wavelength spectrum, and resonator thickness. The sensor with cGST provides better performance. Observing angle of incidence, 95% absorption is noticed with 48-60°radians for wavelength range 0.85-0.98 μm and with 42-69°radians for wavelength range 0.85-0.98 μm. The analysis depicts that the proposed phase change material-based biosensor in general and with cGST, in particular, is suitable for glucose detection in the blood of diabetic patients.