Graphene oxide: a reusable and metal-free carbocatalyst for the one-pot synthesis of 2-amino-3-cyanopyridines in water

Synthesis, characterization, and catalytic application of Fe3O4‐Si‐[CH2]3‐N=CH‐aryl for the efficient synthesis of novel poly‐substituted pyridines

“…These compounds have also attracted considerable attention in recent years because of their wide range of applications such as antimalarial, vasodilatory, anesthetic, anticonvulsant, antifungal, pesticidal, and herbicidal drugs . Various acid or base catalysts, ionic liquids, and nanoparticles had been used for the synthesis of pyridine derivatives . However, most of these methods have limitations such as the use of expensive catalysts or toxic solvents, high reaction time, harsh reaction conditions, and difficult work‐up procedures.…”

“…[18] Various acid or base catalysts, ionic liquids, and nanoparticles had been used for the synthesis of pyridine derivatives. [19][20][21][22][23][24][25][26][27][28][29] However, most of these methods have limitations such as the use of expensive catalysts or toxic solvents, high reaction time, harsh reaction conditions, and difficult work-up procedures. Thus, introducing an environmentally friendly catalytic system for the synthesis of these compounds with more convenient conditions, shorter reaction times, and high yield of products is still of importance.…”

One-Pot-Multicomponent Synthesis of 2,6-Diamino-4-arylpyridine-3,5-dicarbonitrile Derivatives Using Nanomagnetic Fe₃O₄@SiO₂@ZnCl₂

“…Construction of functionalized N-heterocycles utilizing Multicomponent reaction (MCR) strategy has evolved as a new synthetic tool [13][14][15]. N-containing heterocycles show a vast abundance of numerous natural products and several biologically active pharmaceuticals.…”

Synthesis of a novel and reusable biological urea based acidic nanomagnetic catalyst: Application for the synthesis of 2‐amino‐3‐cyano pyridines via cooperative vinylogous anomeric based oxidation

“…These parameters make them versatile apparatus in the different fields of science. [30][31][32][33][34][35][36][37][38][39][40] However, developments of new, mild and applicable approaches for the synthesis of these interesting functionalized nitrogen containing heterocyclic compounds are still valuable. [12][13][14][15][16][17][18] Among the functionalized pyridine systems, 2-amino-3-cyano pyridine derivatives are prevalent.…”

“…[29] In the light of abovmentioned pharmaceutical importance of 2-amino-3-cyano pyridines, diverse protocols have been reported for their preparation. [30][31][32][33][34][35][36][37][38][39][40] However, developments of new, mild and applicable approaches for the synthesis of these interesting functionalized nitrogen containing heterocyclic compounds are still valuable.…”