Graphene oxide/alginate/silk fibroin composite as a novel bionanostructure with improved blood compatibility, less toxicity and enhanced mechanical properties

Chitosan hydrogel/silk fibroin/Mg(OH)2 nanobiocomposite as a novel scaffold with antimicrobial activity and improved mechanical properties

“…Extraction process of SF. Conforming to the previous studies about the degumming treatment methods and extraction of silk fibroin 45,52,53 , first, the silkworm cocoons were cut in to small pieces. Afterwards, in a determined aqueous solution of Na 2 CO 3 (0.21% w/v), the cocoon pieces were boiled during 2 h in order to remove the glue like sericin proteins from the cocoon structure.…”

“…According to previous research works and some corrections 45,55 , to modify the CTT-CS hydrogel, in a small scale, 0.6 mL of SF solution was added to the 0.6 mL of CTT-CS hydrogel solution. Two mentioned solutions were mixed and kept under the stirring condition for 1 h. After the mentioned time, to pre-prepare the suspension mixture for freeze-drying process, the obtained CTT-CS/SF hydrogel was poured into a petri dish and it was kept at freezer (− 70 °C) for 24 h. Afterwards, the freezed petri dish was put in to the freeze-dryer device (shelve) in order to conduct the solvent sublimation process during 24 h. In addition, it should be mentioned that this dehydration process was conducted due to considering a determined temperature condition (− 60 °C) and 0.1 bar pressure.…”

Investigation of the biological activity, mechanical properties and wound healing application of a novel scaffold based on lignin–agarose hydrogel and silk fibroin embedded zinc chromite nanoparticles

“…3 So far, a diverse range of non-natural and natural-based polymers with different applications such as catalysis with high yield efficiency [4][5][6] and adsorption of heavy metal ions 7 have been applied. On the other hand, different biomedical approaches such as tissue engineering, 8,9 drug delivery systems, [10][11][12] hyperthermia cancer therapy, 13,14 and wound healing 15,16 have been exclusively developed by using these types of material. Also, the formation of polymer-based nanomaterials as new biosensing probes has led to advanced detection of pathogenic viruses, 17,18 toxic mycotoxins, 19 neurotoxic proteins, 20 and cancer biomarkers.…”

Design and synthesis of a novel nanocomposite based on magnetic dopamine nanoparticles for purification of α-amylase from the bovine milk

“…0.1–1.0% of each sample was well mixed into 200–250 mg of fine KBr powder for preparation of sample pellets. Considering the spectral resolution (4 cm −1 ) and a determined frequency range (400–4000 cm −1 ), each spectrum was taken at room temperature and the average number of scans was between 6 and 18 32 .…”