Graphene oxide and oxidized carbon nanodiscs as biomedical scaffolds for the targeted delivery of quercetin to cancer cells

Zygouri, Panagiota; Tsiodoulos, Grigorios; Angelidou, Marina; Papanikolaou, Eirini; Athinodorou, Antrea-Maria; Simos, Yannis V.; Spyrou, Konstantinos; Subrati, Mohammed; Kouloumpis, Antonios; Kaloudi, Angela S.; Asimakopoulos, Georgios; Tsamis, Konstantinos; Peschos, Dimitrios; Vezyraki, Patra; Ragos, Vasileios; Gournis, Dimitrios P.

doi:10.1039/d3na00966a

Nanoscale Adv.

2024

DOI: 10.1039/d3na00966a

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Graphene oxide and oxidized carbon nanodiscs as biomedical scaffolds for the targeted delivery of quercetin to cancer cells

Panagiota Zygouri,

Grigorios Tsiodoulos,

Marina Angelidou

et al.

Abstract: Graphene oxide and oxidized carbon nanodiscs have been utilized as potential nanocarriers of quercetin. The conjugation of quercetin to these nanomaterials further enhanced the cell cycle arrest effects.

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To‐Pack or Not‐to‐Pack: Towards Improved Graphite Electrochemical Oxidation Through Electrode Design

Subrati,

Gutiérrez‐Pineda,

Moya

2024

ChemPlusChem

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ABSTRACT. Fabrication of batch‐wise efficient, user‐ and environmentally‐friendly, and well‐defined yield methods for the synthesis of graphite oxide, the main precursor to graphene oxide and its reduced derivative, is an essential and robust research field, yet is sparingly investigated or innovated in recent years. This Concept review showcases recent advances in the fabrication of electrochemical set ups that meet aforementioned design parameters, wherein working electrode construction is seen to play a key role in shaping the yield characteristics and aiding the mechanistic understanding of efficiency of adopted methods. Particularly, these advances pave the way for new and various tunable design parameters by fabricating different methods of encapsulating graphite powder instead of using conventional bare monolith forms of graphite as working electrode. Encapsulation geometry, pressure, and matrix material, as well as powder size are examples of such tunable design parameters, absent in the monolith methods. The encapsulation validates authenticity of real‐time monitoring of electrochemical intercalation, exfoliation, and oxidation of graphite powder, thereby offering excellent and well‐defined control on yield.

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To‐Pack or Not‐to‐Pack: Towards Improved Graphite Electrochemical Oxidation Through Electrode Design

Subrati,

Gutiérrez‐Pineda,

Moya

2024

ChemPlusChem

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Graphene/carbohydrate polymer composites as emerging hybrid materials in tumor therapy and diagnosis

Zhang,

Wang,

Hou

et al. 2025

International Journal of Biological Macromolecules

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Fabrication of a novel graphene oxide based magnetic nanocomposite and its usage as a highly effectual catalyst for the construction of N,N′-alkylidene bisamides

Zare,

Barzegar,

Rostami

et al. 2024

RSC Adv.

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Graphene oxide and oxidized carbon nanodiscs as biomedical scaffolds for the targeted delivery of quercetin to cancer cells

Abstract: Graphene oxide and oxidized carbon nanodiscs have been utilized as potential nanocarriers of quercetin. The conjugation of quercetin to these nanomaterials further enhanced the cell cycle arrest effects.

Cited by 3 publications

References 44 publications

To‐Pack or Not‐to‐Pack: Towards Improved Graphite Electrochemical Oxidation Through Electrode Design

To‐Pack or Not‐to‐Pack: Towards Improved Graphite Electrochemical Oxidation Through Electrode Design

Graphene/carbohydrate polymer composites as emerging hybrid materials in tumor therapy and diagnosis

Fabrication of a novel graphene oxide based magnetic nanocomposite and its usage as a highly effectual catalyst for the construction of N,N′-alkylidene bisamides

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