Graphene oxide-based NET strategy for enhanced colorimetric sensing of miRNA

Lee, Jieon; Young-Kwan, Kim; Lee, Sang‐Woo; Yoon, Seokjoo; Kim, Woo-keun

doi:10.1016/j.snb.2018.11.149

Cited by 39 publications

(13 citation statements)

References 77 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For these reasons, graphene oxide (GO) becomes a more widely used electrode material, whose surface possesses many carboxylic acid and hydroxyl groups [70] to improve its water-solubility. Many strategies have incorporated GO into the design of miRNA detection biosensors [58,71,72]. To meet the need of immobilization of biological molecules with high biological activity remained, CNTs were used because of their large surface area ratio and intertube attraction energy [73].…”

Section: Newly Developed Methodsmentioning

confidence: 99%

Research advances in the detection of miRNA

Tian

et al. 2019

Journal of Pharmaceutical Analysis

291

152

View full text Add to dashboard Cite

MicroRNAs (miRNAs) are a family of endogenous, small (approximately 22 nucleotides in length), noncoding, functional RNAs. With the development of molecular biology, the research of miRNA biological function has attracted significant interest, as abnormal miRNA expression is identified to contribute to serious human diseases such as cancers. Traditional methods for miRNA detection do not meet current demands. In particular, nanomaterial-based methods, nucleic acid amplification-based methods such as rolling circle amplification (RCA), loop-mediated isothermal amplification (LAMP), strand-displacement amplification (SDA) and some enzyme-free amplifications have been employed widely for the highly sensitive detection of miRNA. MiRNA functional research and clinical diagnostics have been accelerated by these new techniques. Herein, we summarize and discuss the recent progress in the development of miRNA detection methods and new applications. This review will provide guidelines for the development of follow-up miRNA detection methods with high sensitivity and specificity, and applicability to disease diagnosis and therapy.

show abstract

Section: Newly Developed Methodsmentioning

confidence: 99%

Research advances in the detection of miRNA

Tian

et al. 2019

Journal of Pharmaceutical Analysis

291

152

View full text Add to dashboard Cite

show abstract

“…The traditional miRNA detection method is very complex and expensive. Lee and colleagues developed a network strategy for the graphene-based colorimetric detection of miRNA with high sensitivity [68]. Through graphene network capture and collection of miRNA, an miRNA/graphene composite network was built, which improved the colorimetric performance.…”

Section: Detection Of Dna/rnamentioning

confidence: 99%

Two-Dimensional Material-Based Colorimetric Biosensors: A Review

2021

View full text Add to dashboard Cite

Two-dimensional (2D) materials such as graphene, graphene oxide, transition metal oxide, MXene and others have shown high potential for the design and fabrication of various sensors and biosensors due to their 2D layered structure and unique properties. Compared to traditional fluorescent, electrochemical, and electrical biosensors, colorimetric biosensors exhibit several advantages including naked-eye determination, low cost, quick response, and easy fabrication. In this review, we present recent advances in the design, fabrication, and applications of 2D material-based high-performance colorimetric biosensors. Potential colorimetric sensing mechanisms and optimal material selection as well as sensor fabrication are introduced in brief. In addition, colorimetric biosensors based on different 2D materials such as graphene, transition metal dichalcogenide/oxide, MXenes, metal–organic frameworks, and metal nanoplates for the sensitive detection of DNA, proteins, viruses, small molecules, metallic ions, and others are presented and discussed in detail. This work will be helpful for readers to understand the knowledge of 2D material modification, nanozymes, and the synthesis of hybrid materials; meanwhile, it could be valuable to promote the design, fabrication, and applications of 2D material-based sensors and biosensors in quick bioanalysis and disease diagnostics.

show abstract

“…Finally, the DNAzyme catalyzed a hemin-based colorimetric reaction. The method had an LOD of 12.9 nM [ 104 ]. Another electrochemical system involved the immobilization of a DNA probe on an electrode.…”

Section: Nanomaterials Used In Liquid Biopsy Applicationsmentioning

confidence: 99%

Nanotechnology in emerging liquid biopsy applications

Kalogianni

2021

Nano Convergence

View full text Add to dashboard Cite

Liquid biopsy is considered as the most attractive alternative to traditional tissue biopsies. The major advantages of this approach lie in the non-invasive procedure, the rapidness of sample collection and the potential for early cancer diagnosis and real-time monitoring of the disease and the treatment response. Nanotechnology has dynamically emerged in a wide range of applications in the field of liquid biopsy. The benefits of using nanomaterials for biosensing include high sensitivity and detectability, simplicity in many cases, rapid analysis, the low cost of the analysis and the potential for portability and personalized medicine. The present paper reports on the nanomaterial-based methods and biosensors that have been developed for liquid biopsy applications. Most of the nanomaterials used exhibit great analytical performance; moreover, extremely low limits of detection have been achieved for all studied targets. This review will provide scientists with a comprehensive overview of all the nanomaterials and techniques that have been developed for liquid biopsy applications. A comparison of the developed methods in terms of detectability, dynamic range, time-length of the analysis and multiplicity, is also provided.

show abstract

Graphene oxide-based NET strategy for enhanced colorimetric sensing of miRNA

Cited by 39 publications

References 77 publications

Research advances in the detection of miRNA

Research advances in the detection of miRNA

Two-Dimensional Material-Based Colorimetric Biosensors: A Review

Nanotechnology in emerging liquid biopsy applications

Contact Info

Product

Resources

About