Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells

Interaction of graphene and WS2with neutrophils and mesenchymal stem cells: implications for peripheral nerve regeneration

“…[100][101][102] Xiaoli and coworkers reported an increased mitochondrial stress with a reduction in the membrane potential (Δψ m ). 101 A positively charged polyethylenimine (PEI)-functionalized GO was also shown to promote mitochondrial fragmentation and cell apoptosis. 100 However, these studies were conducted by incubating the cells with GO or graphene flakes, a completely different condition compared to cells seeded on planar GBMs.…”

Engineering graphene-based electrodes for optical neural stimulation

“…3c). Although cytotoxicity of GBMs to SH-SY5Y cells has been linked to mitochondrial dysfunction via the generation of reactive oxygen species (ROS), 90 no significant oxidative stress was observed after treatment with graphene-UCNP composites (Fig. S6, ESI †).…”

Advances in Graphene Platforms for Drug Delivery in Cancer and Its Biocompatibility

“…However, when GQDs are coated with polyethylene glycol at concentrations of 320 μg/mL, they do not affect the viability and differentiation capacity of neural stem/progenitor cells (NSPCs) [83]. Also, reduced toxicity, absence of ROS production, absence of apoptosis, and lack of morphological changes have been observed in HeLa and A549 tumor cells under concentrations of 100 μg/mL [84,85].…”