Graphene oxide reinforced biopolymeric (chitosan) hydrogels for controlled cephradine release

Qureshi, Muhammad Anees ur Rehman; Arshad, Nasima; Rasool, Atta

doi:10.1016/j.ijbiomac.2023.124948

Cited by 9 publications

(4 citation statements)

References 58 publications

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“…The material was most effective against Escherichia coli and Pseudomonas aeruginosa. Furthermore, pH-responsive swelling (schematic diagram presented in Figure 5) and biodegradability were confirmed in phosphate-buffered saline and proteinase K solutions [80]. Breast cancer is one of the most common cancers in women and has a high mortality rate.…”

Section: Drug Deliverymentioning

confidence: 72%

“…The material was most effective against Escherichia coli and Pseudomonas aeruginosa. Furthermore, pH-responsive swelling (schematic diagram presented in Figure 5) and biodegradability were confirmed in phosphate-buffered saline and proteinase K solutions [80]. Li W. et al [79] constructed a rectal delivery system using temperature-sensitive hydroxybutyl chitosan gel cross-linked with GO with pingyangmycin as a model drug.…”

Section: Drug Deliverymentioning

confidence: 90%

“…Figure 5. Schematic diagram for swelling of hydrogel due to charge zones at polymeric chains (reprinted from[80], with permission from Elsevier, license number: 5611930020590).…”

mentioning

confidence: 99%

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Graphene Production and Biomedical Applications: A Review

Malisz,

Świeczko-Żurek

2023

Crystals

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Graphene is a two-dimensional nanomaterial composed of carbon atoms with sp2 hybrid orbitals. Both graphene and graphene-based composite have gained broad interest among researchers because of their outstanding physiochemical, mechanical, and biological properties. Graphene production techniques are divided into top-down and bottom-up synthesis methods, of which chemical vapor deposition (CVD) is the most popular. The biomedical applications of graphene and its composite include its use in sensors, implantology, and gene and drug delivery. They can be used for tissue engineering, anticancer therapies, and as antimicrobial agents in implant application. The biocompatibility of graphene-based nanomaterials enables their use in the field of biomedicine. This article reviews the properties of graphene, the methods used to produce it, the challenges associated with its use, and the potential applications of this material in biomedicine, regenerative medicine, and drug delivery systems.

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Section: Drug Deliverymentioning

confidence: 72%

“…The material was most effective against Escherichia coli and Pseudomonas aeruginosa. Furthermore, pH-responsive swelling (schematic diagram presented in Figure 5) and biodegradability were confirmed in phosphate-buffered saline and proteinase K solutions [80]. Li W. et al [79] constructed a rectal delivery system using temperature-sensitive hydroxybutyl chitosan gel cross-linked with GO with pingyangmycin as a model drug.…”

Section: Drug Deliverymentioning

confidence: 90%

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Graphene Production and Biomedical Applications: A Review

Malisz,

Świeczko-Żurek

2023

Crystals

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“…Graphene oxide (GO) incorporated in hydrogel frameworks not only improves the mechanical properties, but also increases stabilities and surface area for loading and release of nutrients, drugs and fertilizers etc. [35,36]. Boron is an important micronutrient necessary for crop growth, quality and yield.…”

Section: Introductionmentioning

confidence: 99%

Guar gum/poly ethylene glycol/graphene oxide environmentally friendly hybrid hydrogels for controlled release of boron micronutrient

Azeem,

Islam,

Khan

et al. 2023

R. Soc. open sci.

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The present study was aimed at synthesis of polymeric hydrogels for controlled boron (B) release, as B deficiency is a major factor that decreases crops yield. Thus, graphene oxide incorporated guar gum and poly (ethylene glycol) hydrogels were prepared using the Solution Casting method for boron release. 3-Glycidyloxypropyl trimethoxysilane (GLYMOL) was used as a cross-linker. Characterizations of hydrogels were carried out by Fourier Transform Infrared Spectroscopy (FTIR), Thermo-Gravimetric Analysis and Scanning Electron scope. The FTIR outcomes confirmed the existence of functional groups, bindings and development of hydrogel frameworks from incorporated components. The quantity of GLYMOL directly increased the thermal stability and water retention but decreased the swelling %. The maximum swelling for the hydrogel formulations was observed at pH 7. The addition of GLYMOL changed the diffusion from quasi-Fickcian to non-Fickcian diffusion. The maximum swelling quantities of 3822% and 3342% were exhibited by GPP (control) and GPP-8 in distilled water, respectively. Boron release was determined in distilled water and sandy soil by azomethine-H test using UV-Visible spectrophotometer while 85.11% and 73.65% boron was released from BGPP-16, respectively. In short, water retentive, water holding capacities, swelling performances, biodegradability and swelling/deswelling features would offer an ideal platform for boron release in sustained agricultural applications.

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Phytoremediation of soil co‐contaminated with uranium and chromium by sunflower (Helianthus annuus L.) enhanced with slow‐release composite chelating agent (EDTA/ammonium citrate)

Lin,

Wang,

Zhou

et al. 2024

J of Chemical Tech & Biotech

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BACKGROUNDSoil in uranium mining areas is contaminated by uranium and associated heavy metals, posing a significant threat to human health and ecological security. Chelating agent assisted phytoremediation is a cost‐effective and ecologically friendly remediation approach for uranium and associated heavy metals contaminated soil. In this work, a novel slow‐release composite chelating agent (SRCMC‐g‐CMCD‐EDTA/AC) was fabricated using carboxymethyl chitosan‐graft‐carboxymethyl‐β‐cyclodextrin (CMC‐g‐CMCD) as a slow‐release carrier and EDTA/ammonium citrate (AC) as a composite chelating agent through the spray drying method, which was used for phytoremediation of soil co‐contaminated with uranium and chromium.RESULTSCMC‐g‐CMCD exhibited superior slow‐release performance for both EDTA and AC in comparison with CMC and CMCD. When applied to soil contaminated with uranium (U) and chromium (Cr), SRCMC‐g‐CMCD‐EDTA/AC effectively regulated the release of U and Cr. Sunflowers (Helianthus annuus L.) grown in treated soil showed a significant increase in U and Cr uptake by 70.55% and 35.55%, respectively, and reduced leaching losses by 34.88% and 37.42%.CONCLUSIONSRCMC‐g‐CMCD‐EDTA/AC not only assists in the phytoremediation of soil co‐contaminated with U and Cr but also reduces the risk of leaching into groundwater during the soil phytoremediation process. SRCMC‐g‐CMCD‐EDTA/AC‐assisted phytoremediation technology was an effective and environmentally friendly remediation means for the removal of U and heavy metals from contaminated soils in uranium mining areas. © 2024 Society of Chemical Industry (SCI).

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Graphene oxide reinforced biopolymeric (chitosan) hydrogels for controlled cephradine release

Cited by 9 publications

References 58 publications

Graphene Production and Biomedical Applications: A Review

Graphene Production and Biomedical Applications: A Review

Guar gum/poly ethylene glycol/graphene oxide environmentally friendly hybrid hydrogels for controlled release of boron micronutrient

Phytoremediation of soil co‐contaminated with uranium and chromium by sunflower (Helianthus annuus L.) enhanced with slow‐release composite chelating agent (EDTA/ammonium citrate)

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