Graphite Plate for Pervaporation Wound Therapy

Abstract

Graphitized carbon black is one of the carbon adsorbent biomaterials claimed to treat venomous wounds, but its efficacy has been debate by scientists. We have endeavored to explain the principle of the black stone as a graphite plate in wound therapy. The graphite plate is prepared using cattle bones by pyrolysis and has the ability to create vapor-pressure difference and promoting toxin dehydration in the wound will experience a reduction in pressure. In the process, bacterial membrane disruption and a reduction in reactive oxygen species production around the wound occur. The permanent vapor decrease in the wound then reduces the swelling and bacterial infection on the wound surface, thus stimulating the growth of new tissue around the wound and vaporization of toxin. This promotes the secretion of growth factors that facilitate angiogenesis and extracellular matrix deposition in the wound, thus promoting the release of cytokines for immune response regulation around the wound. The graphite plate can also affect the microenvironment around the wound including pH, temperature and reactive oxygen levels. The graphite plate pervaporation is a promising, effective technique for the removal of trace amounts of organic material and infections introduced in the wound.