This research work proceeds from the assumption, which was still considered by Einstein, that the quantization of gravity does not require additional external procedures: quantum phenomena can be a consequence of the properties of the universal gravitational interaction, which maps any physical field upon the space-time geometry. Therefore, an attempt is made in this research work to reduce the quantization of physical fields in GRT to the space-time quantization. Three reasons for quantum phenomena are considered: Partition of space-time into a set of unconnected Novikov's R-and T-domains impenetrable for light paths; the set is generated by the invariance of Einstein's equations with respect to dual mappings; The existence of electric charge quanta of wormholes, which geometrically describe elementary particles in GRT. This gives rise to a discrete spectrum of their physical and geometric parameters governed by Diophantine equations. It is shown that the fundamental constants (electric charge, rest masses of an electron and a proton) are interconnected arithmetically; The existence of the so-called Diophantine catastrophe, when fluctuations in the values of physical constants tending to zero lead to fluctuations in the number of electric charges and the number of nucleons at the wormhole throats, which tend to infinity, so that the product of the increments of these numbers by the increment of physical constants forms a relation equivalent to the uncertainty relation in quantum mechanics. This suggests that space-time cannot but fluctuate, and, moreover, its fluctuations are bounded from below, so that all processes become chaotic, and the observables become averaged over this chaos.