Gray matter abnormalities in Internet addiction: A voxel-based morphometry study

Zhou, Yan; Lin, Fei; Du, Yasong; Qin, Ling-di; Zhao, Zhenmin; Xu, Jianrong; Lei, Hao

doi:10.1016/j.ejrad.2009.10.025

Cited by 255 publications

(212 citation statements)

References 26 publications

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“…En los últimos años, el uso patológico de internet ha trascendido la consideración de trastorno del control de impulsos (Young, 1999) para encuadrarse en las adicciones comportamentales (Griffiths, 2000), aceptando que tiene una base común con el resto de conductas adictivas (Brezing, Derevensky y Potenza, 2010;Goldstein y Volkow, 2011;Grant, Potenza, Weinstein y Gorelick, 2010;Kormas, Critselis, Janikian, Kafetzis y Tsitsika, 2011;Montag, Kirsch, Sauer, Markett y Reuter, 2012;Zhou et al, 2011). El DSM-5 (APA, 2013) incluye el juego patológico en los trastornos adictivos y el Trastorno por Juego en Internet (Internet Gaming Disorder) en el apartado condiciones para más estudios en el futuro (Sección III).…”

Section: Uso Y Abuso De Sustancias Psicotrópicas E Internet Psicopatunclassified

Uso y abuso de sustancias psicotrópicas e internet, psicopatología e ideación suicida en adolescentes

et al. 2017

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Section: Uso Y Abuso De Sustancias Psicotrópicas E Internet Psicopatunclassified

Uso y abuso de sustancias psicotrópicas e internet, psicopatología e ideación suicida en adolescentes

et al. 2017

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“…In a large study of less severe problem gamblers, no group differences were observed in brain volumes [van Holst et al, 2012]. One small study in internet addiction showed lower cortical thickness in the OFC [Hong et al, 2013], with another reporting lower volume in dorsolateral prefrontal cortex (DLPFC) [Yuan et al, 2011] and two studies suggesting lower ACC volumes [Yuan et al, 2011; Zhou et al, 2011]. Two small studies in internet gaming disorders reported decreased volumes in OFC [Weng et al, 2013; Yuan et al, 2013], and two larger studies reported smaller volumes in cingulate cortex [Lin et al, 2014; Wang et al, 2015] with single studies reporting decreases in DLPFC [Wang et al, 2015], inferior frontal [Lin et al, 2014], superior parietal [Wang et al, 2015] and inferior parietal [Yuan et al, 2013] cortices.…”

Section: Introductionmentioning

confidence: 99%

Compulsive sexual behavior: Prefrontal and limbic volume and interactions

Schmidt

Morris

Kvamme

et al. 2016

Human Brain Mapping

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BackgroundCompulsive sexual behaviors (CSB) are relatively common and associated with significant personal and social dysfunction. The underlying neurobiology is still poorly understood. The present study examines brain volumes and resting state functional connectivity in CSB compared with matched healthy volunteers (HV).MethodsStructural MRI (MPRAGE) data were collected in 92 subjects (23 CSB males and 69 age‐matched male HV) and analyzed using voxel‐based morphometry. Resting state functional MRI data using multi‐echo planar sequence and independent components analysis (ME‐ICA) were collected in 68 subjects (23 CSB subjects and 45 age‐matched HV).ResultsCSB subjects showed greater left amygdala gray matter volumes (small volume corrected, Bonferroni adjusted P < 0.01) and reduced resting state functional connectivity between the left amygdala seed and bilateral dorsolateral prefrontal cortex (whole brain, cluster corrected FWE P < 0.05) compared with HV.ConclusionsCSB is associated with elevated volumes in limbic regions relevant to motivational salience and emotion processing, and impaired functional connectivity between prefrontal control regulatory and limbic regions. Future studies should aim to assess longitudinal measures to investigate whether these findings are risk factors that predate the onset of the behaviors or are consequences of the behaviors. Hum Brain Mapp 38:1182–1190, 2017. © 2016 Wiley Periodicals, Inc.

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“…17,23 Additionally, the lack of formal diagnostic criteria to assess IA represents another methodological problem, since researchers are systematically adopting modified criteria for pathological gambling to investigate IA. 24 Although IA may share some commonalities with other substance-based addictions, [25][26][27] it is unclear to what extent such criteria are useful and suitable to evaluate IA. Notwithstanding the existing difficulties in understanding and comparing IA and pathological gambling, recent research provided useful insights on this topic.…”

Section: A Critical Approach To Definition and Characterizationmentioning

confidence: 99%

Clinical psychology of Internet addiction: a review of its conceptualization, prevalence, neuronal processes, and implications for treatment

Pontes¹,

Kuss²,

Griffiths³

2015

NAN

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Abstract:Research into Internet addiction (IA) has grown rapidly over the last decade. The topic has generated a great deal of debate, particularly in relation to how IA can be defined conceptually as well as the many methodological limitations. The present review aims to further elaborate and clarify issues that are relevant to IA research in a number of areas including: definition and characterization, incidence and prevalence rates, associated neuronal processes, and implications for treatment, prevention, and patient-specific considerations. It is concluded that there is no consensual definition for IA. Prevalence rates among nationally representative samples across several countries vary greatly (from 1% to 18.7%), most likely reflecting the lack of methodological consistency and conceptual rigor of the studies. The overlaps between IA and other more traditional substance-based addictions and the possible neural substrates implicated in IA are also highlighted. In terms of treatment and prevention, both psychological and pharmacological treatments are examined in light of existing evidence alongside particular aspects inherent to the patient perspective. Based on the evidence analyzed, it is concluded that IA may pose a serious health hazard to a minority of people.

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Gray matter abnormalities in Internet addiction: A voxel-based morphometry study

Cited by 255 publications

References 26 publications

Uso y abuso de sustancias psicotrópicas e internet, psicopatología e ideación suicida en adolescentes

Uso y abuso de sustancias psicotrópicas e internet, psicopatología e ideación suicida en adolescentes

Compulsive sexual behavior: Prefrontal and limbic volume and interactions

Clinical psychology of Internet addiction: a review of its conceptualization, prevalence, neuronal processes, and implications for treatment

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