Gray scale and color flow Doppler characterization of uterine tumors.

Carter, Jonathan; Lau, Manbot; Saltzman, Andrew K.; Hartenbach, Ellen M.; Chen, M D; Johnson, P R; Fowler, Jeffrey M.; Carlson, Jay W.; Carson, Linda F.; Twiggs, Leo B.

doi:10.7863/jum.1994.13.11.835

Cited by 18 publications

(5 citation statements)

References 4 publications

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“…Some studies suggest that transvaginal ultrasound scanning in combination with color flow Doppler may assist in the diagnosis of endometrial cancer, as blood flow is increased in malignancies (28)(29)(30)(31). However, increased blood flow has also been reported in benign conditions and results are conflicting whether Doppler sonography improves diagnosis of premalignant and malignant endometrial lesions (32)(33)(34)(35).…”

Section: Transvaginal Ultrasound Scanningmentioning

confidence: 99%

Menorrhagia: an update

Oehler

Rees

2003

Acta Obstet Gynecol Scand

140

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Menorrhagia is defined as a 'complaint of heavy cyclical menstrual bleeding occurring over several consecutive cycles'. Objectively it is a total menstrual blood loss equal to or greater than 80 ml per menstruation. It is estimated that approximately 30% of women complain of menorrhagia. Excessive bleeding is the main presenting complaint in women referred to gynecologists and it accounts for two-thirds of all hysterectomies, and most of endoscopic endometrial destructive surgery. Thus, menorrhagia is an important healthcare problem. Its etiology, investigation, medical and surgical management are described. In approximately 50% of cases of menorrhagia no pathology is found at hysterectomy. Abnormal levels of prostaglandins or the fibrinolytic system in the endometrium have been implicated. Effective medical treatments suitable for long-term use include intrauterine progestogens, antifibrinolytic agents (tranexamic acid) and nonsteroidal anti-inflammatory agents (mefenamic acid). Over the past decade there has been increasing use of endometrial destructive techniques as an alternative to hysterectomy. Their further refinement and the advent of fibroid embolization has increased the options available to women.

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Section: Transvaginal Ultrasound Scanningmentioning

confidence: 99%

Menorrhagia: an update

Oehler

Rees

2003

Acta Obstet Gynecol Scand

140

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“…These findings are consistent with prior studies indicating endometrial flow characteristics are not sufficiently sensitive, specific, or predictive to be used alone as sole criteria for prediction of malignancy. 6,22 Kurjak et al 23 demonstrated tumoral blood flow to be present in 91% of endometrial carcinomas, a much higher rate than in our experience, possibly related to sample size differences, differences in the criteria or techniques used, as well as their utilization of a gold standard of a hysterectomy specimen being the only specimen sampled in every case.…”

Section: Discussionmentioning

confidence: 52%

Practical Utility of Color Doppler Sonography in the Evaluation of Endometrial Pathology

Runner

Gerscovich

Fodor³

et al. 2014

Journal of Diagnostic Medical Sonography

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The sonographic findings and corresponding pathology reports of 83 premenopausal and 55 postmenopausal women were retrospectively reviewed to evaluate the significance of color Doppler imaging in the evaluation of the endometrium. Premenopausal women had flow noted in the single malignancy case and in 16 of 21 (76%) polyps, with 7 polyps (33%) presenting as a vascular pedicle. In postmenopausal women, flow was seen in 3 of 5 (60%) malignancies and 5 of 9 (56%) polyps, with 2 polyps (22%) presenting as a vascular pedicle. Postmenopausal women with thin endometria had flow in 1 of 2 (50%) polyps, while those with thicker endometria had flow in 4 of 7 (56%) polyps and 3 of 5 (60%) malignancies. The data showed that color Doppler imaging was useful in detecting vascular pedicles in endometrial polyps, but it was not otherwise helpful as an independent predictor of malignancy.

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“…Numerous studies have now been published on CFD assessment of gynecologic tumors (5,6,9,12–19) . There is little doubt that the neovascularization associated with malignancy can be visualized by CFD.…”

Section: Discussionmentioning

confidence: 99%

“…The role of color flow Doppler in gynecologic tumor detection has been extensively studied. Tumor sites receiving most attention include the ovary and uterine corpus, while little has been published on cervical tumors (8–10) .…”

mentioning

confidence: 99%

Cervical tumor characterization by transvaginal color flow Doppler ultrasound

Carter

1999

Int J Gynecol Cancer

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The aim of the study was to investigate the blood flow characteristics of benign cervical lesions and invasive cervical tumors and to determine if invasive cervical tumors can be predicted by transvaginal sonography (TVS) and color flow Doppler (CFD). The study design incorporated an open prospective collection of data from patients attending the Women's Cancer Center, University of Minnesota and the Sydney Women's Cancer Center. Inclusion criteria included patients with known benign or malignant cervical pathology. The study group of 66 patients comprised 32 patients with invasive cervical cancer and 34 patients with benign cervical lesions. Benign cervixes were significantly more likely to have absent or normal flow whereas malignant lesions were significantly more likely to have abnormal or increased flow (P < 0.0001). No differences in the uterine or intratumor systolic, diastolic, or mean velocity were found between the two groups. A reduction in the uterine artery pulsatility index (PI) and resistance index (RI) from 1.84 to 1.55 and 0.73 to 0.71, respectively, and also in the intracervical PI from 1.5 to 1.1, in the benign compared to invasive group was found, none of which reached statistical significance. However the intracervical RI was statistically lower (0.62) in malignant tumors compared to patients with benign lesions (0.71) (P = 0.03). The effect of menopause on blood flow characteristics was variable and overall not significant. While the uterine artery systolic velocity was significantly higher in premenopausal women, no such effect was found for the diastolic or mean velocity or the PI and RI. In postmenopausal women, the intratumor PI and RI were higher compared to premenopausal women. In conclusion, transvaginal CFD analysis of the uterine arterial or intratumor bed does not appear to be beneficial in attempting to distinguish benign from malignant cervical tumors.

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Gray scale and color flow Doppler characterization of uterine tumors.

Cited by 18 publications

References 4 publications

Menorrhagia: an update

Menorrhagia: an update

Practical Utility of Color Doppler Sonography in the Evaluation of Endometrial Pathology

Cervical tumor characterization by transvaginal color flow Doppler ultrasound

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