Great potential of renal progenitor cells in kidney: From the development to clinic

Bahrami, Maryam; Darabi, Shahram; Roozbahany, Navid Ahmady; Abbaszadeh, Hojjat Allah; Moghadasali, Reza

doi:10.1016/j.yexcr.2023.113875

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2024

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“…By secreting erythropoietin, CD 133+ progenitor cells can limit renal fibrosis after injury [ 6 ]. Other therapeutic factors effective in kidney injury have been reported to be secreted by renal progenitor cells as vesicles and microvesicles [ 39 , 55 , [62] , [63] , [64] ]. Functional analysis of EV proteins secreted from CD 133 + cells in a study identified a set of proteins related to cell maintenance and cell cycle, negative regulation of apoptosis, specific proteins related to protection against oxidative stress such as SOD, and proteins related to angiogenesis as Von Willebrand [ 56 , 65 ].…”

Section: Discussionmentioning

confidence: 99%