Greater Reductions in Total and Low Density Lipoprotein Cholesterol Are Associated With Concomitant Development of Statin Myopathy

Statin-induced Myopathy

“…(16) The reported incidence of muscle symptoms in statin trials suggests that the frequency of symptoms relates to the potency of the statin employed. (12) There may be a relationship between the incidence of statinassociated myopathy and the extent of reduction in total and LDL cholesterol (17) although this is not supported by the results of clinical trials or clinical experience. (18) There is no standard definition of statin myopathy nor is there any test that conclusively proves the diagnosis.…”