Greek measles epidemic strain, 2005–2006

Papa, Anna; Exindari, Maria; Melidou, Angeliki; Chatzidimitriou, Dimitrios; Karabaxoglou, D.; Antoniadis, Antonios; Kyriazopoulou, V

doi:10.1017/s0950268806007308

Cited by 4 publications

(2 citation statements)

References 12 publications

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“…Most children who developed measles in our study were unvaccinated or partially vaccinated as also reported in previous measles epidemics in Greece [5,20]. These results are similar to results described in other European studies experienced large outbreaks at the same period [11,21,22].…”

Section: Plos Onesupporting

confidence: 91%

Measles epidemic in pediatric population in Greece during 2017–2018: Epidemiological, clinical characteristics and outcomes

et al. 2021

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Background and aim A measles outbreak occurred in Greece during 2017–2018 affecting mainly pediatric population. The aim of the study was to describe the epidemiological and clinical characteristics of the cases diagnosed in the major pediatric tertiary hospital of Athens, where 26.5% of national pediatric measles cases were diagnosed and treated. Methods This is a retrospective study of children 0–16 years old, who presented at the emergency department and/or were hospitalized with clinical presentation compatible with measles and diagnosis was confirmed with molecular detection of the measles RNA in pharyngeal swabs. Epidemiological, clinical and laboratory characteristics were retrieved from medical records and analyzed. Results A total of 578 children with measles were identified during the study period. 322 (55.7%) were male with median age 36 months (range:1–193), while the largest number of documented cases (251; 43.4%) were children aged 1–5 years. Most children (429/578; 74.2%) belonged to the Roma minority and only 64 (11.1%) had Greek origin. 497 (91.5%) children were unvaccinated and 37 (6.8%) were partially vaccinated with measles vaccine. Hospitalization was required for 342 (59.2%) children, whereas one or more complications were reported in 230 (67.2%) of them. Most frequent complications were elevated transaminases (139; 40.6%), acute otitis media (72; 21%), dehydration (67; 19.6%) and pneumonia (58; 16.9%). 11 children (3.2%) required intensive care admission for altered mental status/status epilepticus (3), sepsis (2) and ARDS (6). 119/342 (34.8%) children were treated with antibiotics because of possible or confirmed bacterial coinfection. One death was reported, concerning an 11-month-old unvaccinated infant, with underlying dystrophy, who died of sepsis. Conclusion Measles is not an innocent viral infection, as it is still characterized by high morbidity and complications rates. Unvaccinated or partially vaccinated populations could trigger new outbreaks, resulting in significant cost in public health. To avoid future measles outbreaks, high vaccination coverage should be achieved, as well as closing immunity gaps in the population and ensuring high-quality measles surveillance.

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Section: Plos Onesupporting

confidence: 91%

Measles epidemic in pediatric population in Greece during 2017–2018: Epidemiological, clinical characteristics and outcomes

et al. 2021

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“…In Brazil the goal of interrupting the transmission of endemic measles virus (MV) by the end of 2000 using strategies developed by the Pan American Health Organization (PAHO), which included recommendations for vaccination activities, intended to achieve high population immunity together with sensitive surveillance for suspected measles cases, including effective virological and serological surveillance 1,2 . However this strategy was not implemented in many countries of worldwide and measles outbreaks continued occurring 3,4,5 .…”

Section: Introductionmentioning

confidence: 99%

Vírus do sarampo: vigilância molecular de um caso importado em São Paulo, Brasil

Oliveira,

Afonso,

Figueiredo

et al. 2008

Rev Inst Adolfo Lutz

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No estado de São Paulo, Brasil, em função da eficiente estratégia para a vigilância do vírus do sarampo (VS), não houve registro de casos nativos de sarampo no período de 2001 a 2007. No estado de São Paulo foram registrados casos de sarampo importados, sendo 01 paciente em 2001, outro em 2002 e em 2005 foi alvo de investigação uma criança não vacinada, de 18 meses de idade com exantema e febre, que foi admitida em hospital privado. O Centro de Vigilância Epidemiológica descobriu que o irmão desta criança teve uma doença semelhante uma semana antes. A infecção pelo vírus do sarampo foi confirmada no Instituto Adolfo Lutz pela detecção de anticorpo IgM anti-VS, isolamento do vírus por meio de cultivo em células Vero/hSLAM e amplificação de RNA viral por RT-PCR. A região do gene da nucleoproteína do vírus isolado foi amplificada. O resultado da análise filogênica mostrou que o vírus isolado correspondeu ao genótipo D5. Este genótipo circula no continente da Ásia e há relatos sobre sua anterior circulação em São Paulo.

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Cocirculation of genotypes D4 and D6 in Greece during the 2005 to 2006 measles epidemic

Kokotas

Bolanaki

Sgouras

et al. 2008

Diagnostic Microbiology and Infectious Disease

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Greek measles epidemic strain, 2005–2006

Cited by 4 publications

References 12 publications

Measles epidemic in pediatric population in Greece during 2017–2018: Epidemiological, clinical characteristics and outcomes

Measles epidemic in pediatric population in Greece during 2017–2018: Epidemiological, clinical characteristics and outcomes

Vírus do sarampo: vigilância molecular de um caso importado em São Paulo, Brasil

Cocirculation of genotypes D4 and D6 in Greece during the 2005 to 2006 measles epidemic

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