Green and cost-effective synthesis, characterization and DFT studying of silver nanoparticles for improving their biological properties by opium syrup as biomedical drug and good biocompatibility

Shafaei, Amineh; Khayati, Gholam Reza; Hoshyar, Reyhane

doi:10.1080/24701556.2021.1993257

Cited by 1 publication

(1 citation statement)

References 75 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results showed that delphinidin-5-O-β-D-glucoside and delphinidin-3-O-glucoside had the smallest bandgap (figure 5). Since compounds with closer HOMO and LUMO orbital can easily undergo a reaction, these compounds may play a significant role in reducing Ag and selenite ions [50]. The highest HOMO value (-0.…”

Section: Quantum Chemical Studies and Mechanism Of Nanoparticle Synth...mentioning

confidence: 99%

Ocimum tenuiflorum L mediated green synthesis of silver and selenium nanoparticles: antioxidant activity, cytotoxicity and density functional theory studies

Olawale¹,

Ariatti²,

Singh³

2022

Adv. Nat. Sci: Nanosci. Nanotechnol.

View full text Add to dashboard Cite

Inorganic nanoparticles (NPs) have found extensive application in medicine and pharmaceutics. Although chemical synthesis of NPs is the most commonly employed technique, it is often associated with toxicities due to the nature of the precursors and the experimental conditions used. Hence, there is a need for a safer biosynthetic approach. The current study involves the green synthesis of silver (Ag) and selenium (Se) NPs using an aqueous Ocimum tenuiflorum inflorescence extract. Total phenol and HPLC-MS based phytochemical analysis of the extract was performed. NPs were analysed using UV-visible, and Fourier transform infrared (FTIR) spectroscopy, electron microscopy (EM), x-ray diffraction (XRD) and nanoparticle tracking analysis (NTA). Surface plasmon resonance bands at 433 nm and 285 nm confirmed the synthesis of the Ag and SeNPs, respectively. NPs were monodisperse, small (<65 nm), with good stability and significant antioxidant activity. Cytotoxicity evaluated in the human embryonic kidney (HEK293), cervical carcinoma (HeLa) and breast adenocarcinoma (MCF-7) cells showed a dose-dependent trend with Se possessing better biocompatibility in the normal HEK293 cells than Ag. Density functional theory identified anthocyanins (delphinidin-5-O-beta-d-glucoside and delphinidin-3-O-glucoside) to have the most favourable NP-reducing and stabilising potential from the identified plant compounds.

show abstract

Section: Quantum Chemical Studies and Mechanism Of Nanoparticle Synth...mentioning

confidence: 99%

Ocimum tenuiflorum L mediated green synthesis of silver and selenium nanoparticles: antioxidant activity, cytotoxicity and density functional theory studies

Olawale¹,

Ariatti²,

Singh³

2022

Adv. Nat. Sci: Nanosci. Nanotechnol.

View full text Add to dashboard Cite

show abstract

Green and cost-effective synthesis, characterization and DFT studying of silver nanoparticles for improving their biological properties by opium syrup as biomedical drug and good biocompatibility

Cited by 1 publication

References 75 publications

Ocimum tenuiflorum L mediated green synthesis of silver and selenium nanoparticles: antioxidant activity, cytotoxicity and density functional theory studies

Ocimum tenuiflorum L mediated green synthesis of silver and selenium nanoparticles: antioxidant activity, cytotoxicity and density functional theory studies

Contact Info

Product

Resources

About