Green Asymmetric Organocatalysis

Abstract

Scheme12. At extile-supported organocatalyst for anhydride opening; MTBE = methyl tert-butyl ether.Scheme13. Organocatalytic aldolreaction conductedb yu sing the continuous-flow technique.Scheme11. PS-immobilized catalyst C32 for the amination of oxindoles 32.Scheme40. Photo-organocatalytic hydroxylation of ketoesters and amides. LED = light-emitting diode.Scheme41. Light-promoted cyclization.Scheme42. Light-promoted alkylation of aldehydes. EWG = electron-withdrawinggroup.Scheme49. Primary-aminec atalyzed light-promoted alkylations of dicarbonyl compounds.Scheme48. Light-promoted organocatalytic Michael additions.

Asymmetric Organocatalysis in Deep Eutectic Solvents

“…Different methodologies have already been reported with the aim of improving the sustainability of organocatalytic processes [4] . The application of alternative and greener solvents in asymmetric organocatalysis enables the reduction of waste formation generally attributed to the employment of volatile organic compounds (VOCs) as a reaction medium [5] . Deep eutectic solvents (DESs) have recently emerged as promising alternative solvents in organic chemistry since they share the advantages of ionic liquids, such as low vapor pressure and non‐flammability, but are inexpensive and easy to recycle, have a low ecological footprint and their synthesis is straightforward.…”

Heterogeneous Catalysis with the Participation of Ionic Liquids

“…An intensive development can be observed among ionic liquids themselves, as well as among the compounds that are not altogether regarded as ionic liquids such as deep eutectic solvents [35][36][37] or solvate ionic liquids [38]. Currently, the diversity of the application directions is very large, beginning from separation techniques [39] through the production and storage of energy [40,41], different types of biotransformations [42,43], organocatalysis [44], and ending with pharmaceuticals [45] and space technology [46].…”

Recent Advances in Asymmetric Catalytic Electrosynthesis

“…In electrosynthesis, chemical redox reagents are replaced with electricity for the transformation of organic molecules. While dating back to the 19th century, the topic is currently receiving renewed interest due to its enabling potential for selective and sustainable synthesis [11][12][13][14][15][16][17][18][19]. In an electrochemical reaction, oxidation occurs at the anode and reduction at the cathode in a conductive medium.…”