Green-based bio-synthesis of nickel oxide nanoparticles in Arabic gum and examination of their cytotoxicity, photocatalytic and antibacterial effects

Abstract

In the current paper, NiO-NPs were synthesized through a sol-gel method by the usage of a biocompatible polymer known as Arabic gum (GA) as a stabilizing agent. The structural, optical, and magnetic properties of the obtained product was investigated by the application of TGA/ DTA, FT-IR, UV-Vis, XRD, FESEM/EDX, and VSM analyzes. The FESEM images of NiO-NPs displayed its spherical shape and average size of about 59 nm. The antimicrobial activity of NiO-NPs was investigated against Gram-positive bacteria including Staphylococcus aureus, Bacillus subtilis and Gram-negative bacteria including Escherichia coli, Pseudomonas aeruginosa. The achieved findings indicated that all of the bacterial resistance was attributed to NiO-NPs, except for the case of Bacillus subtilis bacteria that did not grow at the concentration of 10 mM. We also evaluated the photocatalytic activity of nanoparticles in regards to the MB degradation and observed a photocatalytic degradation efficiency of about 80% throughout the results. The cytotoxicity of NiO-NPs has evaluated towards the cancer U87MG cell and normal Nervous Neurospheres (NCs) cells lines by means of MTT method. Detailed in vitro biological activities revealed the significant therapeutic potential of NiO-NPs. This product was able to exhibit potent cytotoxicity against U87MG cancer cells (IC 50 : 37.84 μg mL −1 ).

Promising antimicrobial and antibiofilm activities of reduced graphene oxide-metal oxide (RGO-NiO, RGO-AgO, and RGO-ZnO) nanocomposites

“… 13,14 Previous studies have reported that RGO has antimicrobial activity, 15–17 and GO when conjugated with active ingredients exhibits antimicrobial and antinematodal activities. 18,19 Furthermore, metal and metal oxide nanoparticles, such as silver, 20–22 zinc oxide, 23–25 and nickel oxide, 26,27 are widely used as antimicrobials, and a silver boron nano-formulation is a potential nematicide. 28 …”

Functionalized biobased composite for metal decontamination – Insight on uranium and application to water samples collected from wells in mining areas (Sinai, Egypt)

“…Functionalized Arabic gum (frequently associated to other biopolymer) has also been investigated for metal sorption [25,[35][36][37][38][39][40]. Arabic gum was also used as support for designing active materials with antimicrobial properties by deposition of metal oxide nanoparticles [41].…”

Versatile Applications Of Biopolymer Nanocomposites: A review

“…Among all the nano catalysts, PMNPs are specifically appealing because of their high surface area to extent ratios and excellent surface properties, which allowed their catalytic performance to be available. [112] Since catalytic reactions required transition metals, polysaccharides could provide suitable functional properties for dispersing the noble MNPs as hosts and make the dimensions and form of catalysts extra controllable. [1] Thus, numerous studies had highlighted the possibilities of PMNPs in the catalytic application as shown in .…”

“…In this regard, homogeneous catalysts that exhibited excessive selectivity had acquired a whole lot of extra interest. Among all the nano catalysts, PMNPs are specifically appealing because of their high surface area to extent ratios and excellent surface properties, which allowed their catalytic performance to be available [112] . Since catalytic reactions required transition metals, polysaccharides could provide suitable functional properties for dispersing the noble MNPs as hosts and make the dimensions and form of catalysts extra controllable [1] .…”