Green Chemistry: Air-Triggered Catalyst- and Oxidant-Free Decarboxylative Oxysulfonylation of Arylpropiolic Acids With Sodium Sulfinates

Abstract

The exploration of novel green synthetic strategies to obtain useful organic molecules is one of the most important missions for sustainable development. Herein, an efficient and sustainable decarboxylative oxysulfonylation between arylpropiolic acids and sodium sulfinates has been established, providing a broad scope of β-ketosulfones in excellent yields. The reactions proceed at room temperature employing air as the only oxidant and oxygen source without extra catalyst, oxidant, and additive. Additionally, the reaction is scalable, and the products have been easily isolated by simple recrystallization, avoiding the chromatographic purification. Mechanistic studies have also been conducted to reveal that the reaction proceed via a radical mechanism.