Green extraction of essential oils from Pistacia lentiscus resins: Encapsulation into Niosomes showed improved preferential cytotoxic and apoptotic effects against breast and ovarian cancer cells

Newly Synthesized Anticancer Purine Derivatives Inhibiting p-EIF4E Using Surface-Modified Lipid Nanovesicles

“…They are composed mainly of cholesterol and non-ionic surfactants engineered by self-assembly in an aqueous phase, generating bilayer vesicles . Niosomes have attractive properties making them one of the promising nanovesicles in cancer therapy, such as being stable, biocompatible, biodegradable, and safe carriers with minimum immunogenic effects. , In addition, the negatively charged niosomes could be coated with the polycationic chitosan via an electrostatic interaction. Chitosan is a biocompatible and biodegradable natural polymer with mucoadhesive properties.…”

“…Current chemotherapeutics delivery approaches include various nanocarriers, including metallic nanoparticles, polymeric nanoparticles, − macromolecules, , silica nanoparticles, and nanovesicles. , Nanovesicles (liposomes and niosomes) are lipid-based nanocarriers that are reported to encapsulate natural and synthetic chemotherapeutics, enhancing their hydrophilicity and therapeutic effects . Liposomes are formed mainly of phospholipids (such as phosphatidylcholine and phosphatidylethanolamine) self-assembled in an aqueous medium, developing lipid bilayer nanovesicles . On the other hand, niosomes have emerged as a reliable and modern alternative nanocarrier to liposomes.…”

Box–Behnken design of thermo-responsive nano-liposomes loaded with a platinum(iv) anticancer complex: evaluation of cytotoxicity and apoptotic pathways in triple negative breast cancer cells

“…This might be attributed to the electrostatic interactions between the positively charged platinum-based drug (Asp) and the negatively charged liposomes, which led to high entrapment efficiencies. 44 Interactions between factor A and the other two factors were insignicant, as presented in Fig. 2E.…”

Emerging tendencies for the nano-delivery of gambogic acid: a promising approach in oncotherapy

“…Several natural compounds have been reported to exert compelling antitumor activities against various cancer cells through different mechanisms, such as inducing programmed cell death, halting angiogenesis, impeding inflammatory mediators, and initiating autophagic pathways. 7–11 The most prevalent groups of natural compounds with anticancer effects are polyphenols, phytochemicals, and xanthonoids. 12,13 Gambogic acid (GA) is the major xanthone component of the dry resin extracted from the Garcinia hanburyi Hook.…”