Green Extraction of Natural Products: Concept and Principles

Chémat, Farid; Vian, Maryline Abert; Cravotto, Giancarlo

doi:10.3390/ijms13078615

Cited by 1,388 publications

(827 citation statements)

References 11 publications

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“…The cost of SC-CO 2 extraction process has restricted the applications to certain specialized fields such as decaffeinated coffee preparation industries [63] . The main drawbacks remain its high initial investment and difficulties to perform continuous extractions [64] . However, ultrasonic and microwave extraction gave the higher phenolic content.…”

Section: Effect Of Extraction Methods On Radical Scavenging Activitymentioning

confidence: 99%

Comparison of the Efficiency of Different Extraction Methods on Antioxidants of Maltease Orange Peel

Boudhrioua¹

2016

IJFNS

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The effect of conventional solvent extraction, CSE, ultrasound assisted extraction, UAE, microwave assisted extraction, MAE and supercritical CO 2 extraction, SC-CO 2 on the total phenols content, total flavonoids, individual flavonoids and antioxidant activity of orange peel were compared. Neohesperidin (from 0.624 ± 0.013 for SC-CO 2 extraction to 1.045 ± 0.001 g100 g orange peel powder for MAE) and hesperidin (from 0.407 ± 0.008 for SC-CO 2 extraction to 0.836 ± 0.029 g/100 g orange peel powder for UAE) are the major flavonoids (80% of total flavonoids by MAE and 87% by CSE) of orange peel whatever the used extraction method. The method giving the highest total phenol and flavonoid contents is microwave assisted extraction (2.363 ± 0.014 g GAE/100g orange peel powder), followed by ultrasound assisted extraction, conventional solvent extraction, and supercritical CO 2 extraction. However, antioxidant activity (DPPH method) cannot be correlated to TPC, TFC or individual flavonoids. Orange peel extracted by CSE (ethanol (80%), m/v: 5 g:50 ml, 30 min, 35°C, mechanical stirring at darkness, 3 successive extractions) presents the higher radical scavenging capacity compared to the other extracts obtained by MAE (Ethanol (80%), m/v: 5 g: 50 ml, 10s, 35°C, 170 W, 3 successive extractions) and UAE (ethanol (80%), m/v: 5g:50 ml, 30 min, 35°C, magnetic stirring at darkness, 3 successive extractions, 125W), SC-CO 2 extraction (ethanol (80%), m/v:5 g:50 ml, 30 min, 35°C, 22 MPa, 3 successive extractions). Besides, no additivity on the antioxidant activity is found with the DPPH method.

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Section: Effect Of Extraction Methods On Radical Scavenging Activitymentioning

confidence: 99%

Comparison of the Efficiency of Different Extraction Methods on Antioxidants of Maltease Orange Peel

Boudhrioua¹

2016

IJFNS

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“…The recent studies have shown that the ultrasound-assisted extraction of can enhance the extraction efficiency through acoustic cavitation and some mechanical effects (Chemat et al, 2012(Chemat et al, , 2004Rostagno et al, 2003). Acoustic cavitation can disrupt cell walls facilitating solvent to penetrate into the plant material and allowing the intracellular product release.…”

Section: Introductionmentioning

confidence: 99%

Effect of ultrasonic treatment on extraction and fatty acid profile of flaxseed oil

Gutte

Sahoo

Ranveer

2015

OCL

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-The aim of this study was to optimize extracion of flaxseed oil process by ultrasonic treatment and determination of its effect on ω-3 fatty acid. The extraction of flaxseed oil was optimized by using different solvents like methanol, acetone, petroleum ether, ethanol, hexane and dichloromethane. The ultrasonication treatment was optimized with respect to amplitude (20-80 kHz), temperature (25-40 • C), sonication time (20-80 min) and solid to solvent ratio (1:5, 1:10 and 1:15) for extraction of flaxseed oil. The extracted oil was subjected to GC analysis to determine ω-3 fatty acid. The recovery of flaxseed oil was higher with hexane followed by dichloromethane. The ultrasonic treatment at frequency of 40 kHz, temperature of 30 • C, extraction time of 40 min and solid to solvent ratio: 1:10 gave best results for extraction. The ultrasonic assisted extraction improves the extraction yield by 11.5% with similar amount of solvent. The chromatograph showed that there were no significant effects on α-Linolenic acid (ω-3) by the ultrasonic assisted extraction. This will beneficial to the oil extractor to recover higher amount of oil from same amount of the raw materials.

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“…In connection with green extraction of natural products, this definition can be altered as follows: "Green extraction is based on the discovery and design of extraction processes which will reduce energy consumption, allows use of alternative solvents and renewable natural products, and ensure a safe and high quality extract/product" [2].…”

Section: Introductionmentioning

confidence: 99%

“…Currently, all cosmetic, perfume, biofuel, food, pharmaceutical, or fine chemical industries, use extraction procedures such as maceration, decoction, infusion, percolation, pressing, steam or hydro-distillation, and soxhlet extraction. Active principles or their precursors are extracted by pharmaceutical industries by conventional methods or modern technologies [2].…”

Section: Introductionmentioning

confidence: 99%

Spectroscopic Determination of Functionalized Active Principles from Coleus aromaticus Benth Leaf Extract Using Ionic Liquids

2016

IJACEBS

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Abstract-Green chemistry for plant extraction of active principles is the main interest of many researchers concerned with climate change. While classical organic solvents are detrimental to our environment, greener alternatives to ionic liquids are very promising for sustainable organic chemistry. This study focused on the determination of functional groups observed in the main constituents from the ionic liquid extracts of Coleus aromaticus Benth leaves using FT-IR spectroscopy. Moreover, this research aimed to determine the best ionic liquid that can separate functionalized plant constituents from the leaves of Coleus aromaticus Benth using Fourier Trans-form Infrared Spectroscopy. Coleus aromaticus Benth leaf extract in different ionic liquids, elucidated pharma-cologically important functionalized groups present in major constituents of the plant, namely, rosmarinic acid, caffeic acid and chlorogenic acid. In connection to distinctive appearance of functional groups in the spectrum and highest % transmittance, potassium chloride-glycerol is the best ionic liquid for green extraction.

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Green Extraction of Natural Products: Concept and Principles

Cited by 1,388 publications

References 11 publications

Comparison of the Efficiency of Different Extraction Methods on Antioxidants of Maltease Orange Peel

Comparison of the Efficiency of Different Extraction Methods on Antioxidants of Maltease Orange Peel

Effect of ultrasonic treatment on extraction and fatty acid profile of flaxseed oil

Spectroscopic Determination of Functionalized Active Principles from Coleus aromaticus Benth Leaf Extract Using Ionic Liquids

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