Green Route for the Fabrication of ZnO Nanoparticles and Potential Functionalization with Chitosan Using Cross-linkers: A Review

Abstract

Zinc oxide is of significant importance for many industries due to its versatile properties, which have been enhanced with the production of this material in the nanoscale. Recent interest in the preparation of metal oxide nanoparticles using biological approaches has been reported in the literature. This technique known as “green synthesis” is an environmentally benign process than conventional methods like physical and chemical synthesis methods. Zinc oxide nanoparticles (ZnO-NPs) have been successfully obtained by green synthesis using different biological substrates like chitosan. Chitosan is biocompatible, biodegradable polymer having exclusive physical and chemical properties. Chitosan/metal oxide nanocomposite is a promising nanomaterial with enhanced properties for multiple functionalities. Therefore, this review discusses favorable approach in the formation of cross-linked Chitosan/ZnO nanocomposites attracting significant attention in various fields such biomedical due to their unique biodegradable, biocompatible, non-toxic nature. The use of biological sources, fabrication of green synthesized ZnO nanoparticles and its applications is briefly discussed. Overall, this review is a comprehensive study for the synthesis of ZnO-NPs using biological sources counting on their features and applications.

Synthesis and Characterization of Ionically Cross-Linked Chitosan Nanoparticles

“…Numerous natural and synthetic polymers, such as chitosan and polyethyleneimine (PEI), have been used to manufacture nanoparticles that can transport DNA/siRNA or anticancer drugs [3]. With an annual production of more than 100 million tonnes [4], chitosan ranks as the second most prevalent polysaccharide on the planet [5]. It is a copolymer that contains -(1,4)-2-acetamido-D-glucose and -(1,4)-2-amino-D-glucose unit (Figure 1), chitosan is prepared by removing an acetate moiety from chitin through hydration in concentrated alkali [6].…”

Zinc Oxide Nanoparticles-Poly(vinyl) Alcohol Thin Film for Generation Q-Switched Erbium-Doped Fiber Laser

“…Besides having a wide band gap which is beneficial in optical applications, it is also more resistant to radiation damage [9]. Furthermore, in nanoparticles form, it is easily a better alternative for the environment due to its biocompatibility, nontoxicity and pollution-free nature [10][11][12][13], proven by its capability to act as a medium for drugs and cosmetics formulations [14][15].…”