Green Route to Prepare Renewable Polyesters from Monomers: Enzymatic Polymerization

Naolou, Toufik

doi:10.1002/9781118698600.ch7

Cited by 2 publications

(3 citation statements)

References 102 publications

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“…Alternatively, enzymatic polymerization can be used for the synthesis of functional polyesters with different advantages [ 17 , 18 ]. It has emerged as a versatile technique for green polymer synthesis over more than two decades, and where enzymes work as biocatalysts to drive the chemical reaction [ 19 , 20 , 21 , 22 ]. Thus, it avoids the risk of toxicity which can occur due to metal based catalysts (zinc, aluminum, tin, antimony etc.…”

Section: Introductionmentioning

confidence: 99%

Polymer Networks Synthesized from Poly(Sorbitol Adipate) and Functionalized Poly(Ethylene Glycol)

Rashid

Golitsyn

Bilal

et al. 2021

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Polymer networks were prepared by Steglich esterification using poly(sorbitol adipate) (PSA) and poly(sorbitol adipate)-graft-poly(ethylene glycol) mono methyl ether (PSA-g-mPEG12) copolymer. Utilizing multi-hydroxyl functionalities of PSA, poly(ethylene glycol) (PEG) was first grafted onto a PSA backbone. Then the cross-linking of PSA or PSA-g-mPEG12 was carried out with disuccinyl PEG of different molar masses (Suc-PEGn-Suc). Polymers were characterized through nuclear magnetic resonance (NMR) spectroscopy, gel permeation chromatography (GPC), and differential scanning calorimetry (DSC). The degree of swelling of networks was investigated through water (D2O) uptake studies, while for detailed examination of their structural dynamics, networks were studied using 13C magic angle spinning NMR (13C MAS NMR) spectroscopy, 1H double quantum NMR (1H DQ NMR) spectroscopy, and 1H pulsed field gradient NMR (1H PFG NMR) spectroscopy. These solid state NMR results revealed that the networks were composed of a two component structure, having different dipolar coupling constants. The diffusion of solvent molecules depended on the degree of swelling that was imparted to the network by the varying chain length of the PEG based cross-linking agent.

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Section: Introductionmentioning

confidence: 99%

Polymer Networks Synthesized from Poly(Sorbitol Adipate) and Functionalized Poly(Ethylene Glycol)

Rashid

Golitsyn

Bilal

et al. 2021

Gels

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“…The so-called improvements consist of no generation of inhibitor leaving groups (like water), higher molar mass, lower polydispersity and better control of the end group. 40,41 However, the feasibility of an environmentally friendly ROP of lactones at an industrial scale is remote. Just for the obtention of the lactone itself, temperatures of 150-210 C for several hours are needed (under high vacuum).…”

Section: Ring-opening Polymerizationmentioning

confidence: 99%

“…The so‐called improvements consist of no generation of inhibitor leaving groups (like water), higher molar mass, lower polydispersity and better control of the end group 40,41 …”

Section: Synthetic Routes Towards Poly‐esterificationsmentioning

confidence: 99%

Evaluation of biocatalytic pathways in the synthesis of polyesters: Towards a greener production of surgical sutures

Nicolás

Lassalle

Ferreira

2022

Polymers for Advanced Techs

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This review presents an updated and alternative perspective on enzymatic synthesis to obtain polyesters, with a focus on the precursor materials for absorbable sutures: poly‐lactic, poly‐glycolic, and poly‐lactic‐co‐glycolic acids. Currently, the profitable path towards the industrial synthesis of polyesters is ring‐opening polymerization (ROP) of lactones, which is an experimentally complex process and implies a hazardous environmental impact due to the need for energy consumption, use of large volumes of toxic organic solvents and of non‐biocompatible metal‐based catalysts. On the contrary, enzymatically driven reactions may be performed under mild conditions in simple reactors. Mechanistic and experimental issues of the two major biocatalyzed strategies ‐direct condensation and ROP‐ were analyzed from a green chemistry perspective. These enzyme‐catalyzed poly‐esterifications often return low yield and/or low final molecular weight (Mw). Considering all the analyzed published data available, possible strategies to overcome these limitations were postulated: implementation of aqueous biphasic reaction systems, use of ultrasound agitation and sequential addition of reactants or co‐solvents. To promote Mw increment, post‐reaction treatments can be carried out such as thermally induced short‐chain polymerization under vacuum and incorporation of glycols as chain extenders.

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Green Route to Prepare Renewable Polyesters from Monomers: Enzymatic Polymerization

Cited by 2 publications

References 102 publications

Polymer Networks Synthesized from Poly(Sorbitol Adipate) and Functionalized Poly(Ethylene Glycol)

Polymer Networks Synthesized from Poly(Sorbitol Adipate) and Functionalized Poly(Ethylene Glycol)

Evaluation of biocatalytic pathways in the synthesis of polyesters: Towards a greener production of surgical sutures

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