Green silver nanoparticles: enhanced antimicrobial and antibiofilm activity with effects on DNA replication and cell cytotoxicity

Gupta, Kuldeep; Barua, Shaswat; Hazarika, Shabiha Nudrat; Manhar, Ajay Kumar; Nath, Dhrubajyoti; Karak, Niranjan; Namsa, Nima D.; Mukhopadhyay, Rupak; Kalia, Vipin Chandra; Mandal, Manabendra

doi:10.1039/c4ra08791g

Cited by 45 publications

(20 citation statements)

References 52 publications

(48 reference statements)

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“…6 value indicates that the green synthesized silver nanoparticles using the leaf extract of guava can inhibit the growth of P. aeruginosa MTCC 741 strain at the concentration of 10 -6 (M). This study is tuned with earlier reported studies: antibacterial activity of Ag nanoparticles on fish pathogen and other microbes (Gupta et al 2014;Velmurugan et al 2014, Mahanty et al 2013. Several mechanisms regarding antimicrobial activity of Ag nanoparticles have been proposed.…”

Section: Resultsmentioning

confidence: 93%

Biogenic synthesis of silver nanoparticles using guava (Psidium guajava) leaf extract and its antibacterial activity against Pseudomonas aeruginosa

2015

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Among the various inorganic nanoparticles, silver nanoparticles have received substantial attention in the field of antimicrobial research. For safe and biocompatible use of silver nanoparticles in antimicrobial research, the different biogenic routes are developed to synthesize silver nanoparticles that do not use toxic chemicals. Among those, to synthesize silver nanoparticles, the use of plant part extract becomes an emerging field because plant part acts as reducing as well as capping agent. For large-scale production of antibacterial silver nanoparticles using plant part, the synthesis route should be very simple, rapid, cost-effective and environment friendly based on easy availability and non-toxic nature of plant, stability and antibacterial potential of biosynthesized nanoparticles. In the present study, we report a very simple, rapid, cost-effective and environment friendly route for green synthesis of silver nanoparticles using guava (Psidium guajava) leaf extract as reducing as well as capping agent. This plant has been opted for the present study for its known medicinal properties, and it is easily available in all seasons and everywhere. The biosynthesized silver nanoparticles are characterized by UV-Vis and TEM analysis. The average particle size is 40 nm in the range of 10-90 nm. The antibacterial activity of these nanoparticles against Pseudomonas aeruginosa MTCC 741 has been measured by disc diffusion method, agar cup assay and serial dilution turbidity measurement assay. The results show that green synthesized silver nanoparticles, using guava (Psidium guajava) leaf extract, have a potential to inhibit the growth of bacteria.

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Section: Resultsmentioning

confidence: 93%

Biogenic synthesis of silver nanoparticles using guava (Psidium guajava) leaf extract and its antibacterial activity against Pseudomonas aeruginosa

2015

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“…The MIC value indicates that the green synthesized silver nanoparticles using the leaf extract of vasaka can inhibit the growth of P. aeruginosa MTCC 741 strain at the concentration of 10 -5 (M). This study is tuned with earlier reported studies: anti bacterial activity of Ag nanoparticles on fish pathogen and other microbes [3][4][5].…”

Section: Uv-visible Spectroscopymentioning

confidence: 86%

“…It is revealed that bacteria within biofilm are responsible for more than 80 % infectious diseases as well as more resistance to antibiotics [1]. In recent years, due to unique physical and chemical properties of nanoparticles, its uses to disrupt biofilm of bacteria are revolutionary steps in antimicrobial research [2][3][4][5][6][7][8][9][10][11][12][13]. The uses of silver and silver compounds are very well known from ancient time in case of dental work, catheters and burn wounds etc.…”

Section: Introductionmentioning

confidence: 99%

“…The uses of silver and silver compounds are very well known from ancient time in case of dental work, catheters and burn wounds etc. Thus, among the various inorganic metal nanoparticles, silver (Ag) nanoparticles have received substantial attention in the field of biological system, living organisms and medicine [3][4][5][7][8][9][10][11][12][13]. To use in biological field the metal nanoparticles should be biocompatible and free from toxic chemicals which are used to synthesis nanoparticles in traditional chemical process.…”

Section: Introductionmentioning

confidence: 99%

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Antibacterial Activity of Green Synthesized Silver Nanoparticles Using Vasaka (Justicia adhatoda L.) Leaf Extract

Bose¹,

Chatterjee²

2015

Indian J Microbiol

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There is an increasing demand for silver nanoparticles due to its wide applicability in various area of biological science such as in field of antimicrobial and therapeutics, biosensing, drug delivery etc. To use in bioprocess the silver nanoparticles should be biocompatible and free from toxic chemicals. In the present study we report a cost effective and environment friendly route for green synthesis of silver nanoparticles using Vasaka (Justicia adhatoda L.) leaf extract as reducing as well as capping agent. This plant has been opted for the present study for its known medicinal properties and it is easily available. The biosynthesized silver nanoparticles are characterized by UV-Vis spectroscopy and TEM analysis. It is observed the nanoparticles are well shaped and the average particle size is 20 nm in the range of 5-50 nm. The antibacterial activity of these nanoparticles against Pseudomonas aeruginosa MTCC 741 has been measured by disc diffusion method, agar cup assay and serial dilution turbidity measurement assay. The results show green synthesized silver nanoparticles, using Vasaka leaf extract, have a potential to inhibit the growth of bacteria.

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“…Mohanpuria et al [11] have reviewed the synthesis of silver nanoparticles using plants. Gupta et al [12] synthesized silver nanoparticles (AgNPs) using the methanolic extract of Syzygium cumini leaf. The prepared nanoparticles inhibited biofilm formation in a wide range of AgNP concentrations.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Activities of Silver Nanoparticles Synthesized by Using Water Extract of Arnicae anthodium

Dobrucka

Długaszewska

2015

Indian J Microbiol

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Green synthesis of nanoparticles has gained significant importance in recent years and has become the one of the most preferred methods. Also, green synthesis of nanoparticles is valuable branch of nanotechnology. Plant extracts are eco-friendly and can be an economic option for synthesis of nanoparticles. This study presents method the synthesis of silver nanoparticles using water extract of Arnicae anthodium. Formation of silver nanoparticles was confirmed by UV-visble spectroscopy, Fourier transform infrared spectroscopy and total reflection X-ray fluorescence analysis. The morphology of the synthesized silver nanoparticles was verified by SEM-EDS. The obtained silver nanoparticles were used to study their antimicrobial activity.

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Green silver nanoparticles: enhanced antimicrobial and antibiofilm activity with effects on DNA replication and cell cytotoxicity

Abstract: Synthesis of green and biocompatible silver nanoparticles with high anti-microbial and anti-biofilm activities.

Cited by 45 publications

References 52 publications

Biogenic synthesis of silver nanoparticles using guava (Psidium guajava) leaf extract and its antibacterial activity against Pseudomonas aeruginosa

Biogenic synthesis of silver nanoparticles using guava (Psidium guajava) leaf extract and its antibacterial activity against Pseudomonas aeruginosa

Antibacterial Activity of Green Synthesized Silver Nanoparticles Using Vasaka (Justicia adhatoda L.) Leaf Extract

Antimicrobial Activities of Silver Nanoparticles Synthesized by Using Water Extract of Arnicae anthodium

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