Green Synthesis and Antibacterial Activity of Ag/Fe2O3 Nanocomposite Using Buddleja lindleyana Extract

Abstract

In the study reported in this manuscript, silver/iron oxide nanocomposites (Ag/Fe2O3) were phytosynthesized using the extract of Buddleja lindleyana via a green, economical and eco-friendly strategy. The biosynthesized Ag/Fe2O3 nanocomposites were characterized using UV-Vis spectrophotometry, FTIR, XRD, TEM, DLS and SEM-EDX analyses. The particulates showed a triangular and spherical morphology having sizes between 25 and 174 nm. FTIR studies on the nanoparticles showed functional groups corresponding to organic metabolites, which reduce and stabilize the Ag/Fe2O3 nanocomposite. The antimicrobial efficacy of the phytosynthesized Ag/Fe2O3 against bacterial pathogens was assessed. In addition, Ag/Fe2O3 exhibited broad spectrum activities against B. subtilis, S. aureus, E. coli, and P. aeruginosa with inhibition zones of 23.4 ± 0.75, 22.3 ± 0.57, 20.8 ± 1.6, and 19.5 ± 0.5 mm, respectively. The Ag/Fe2O3 composites obtained showed promising antibacterial action against human bacterial pathogens (S. aureus, E. coli, B. subtilis and P. aeruginosa), making them candidates for medical applications.

Role of Iron Oxide (Fe2O3) Nanocomposites in Advanced Biomedical Applications: A State-of-the-Art Review

“…Tumors develop rapidly, accumulating lactic acid and lowering the pH of these areas (pH 4–6) in comparison to physiological status (pH 7.4) [ 50 , 60 ]. The highly expanded surface area, appropriate porosity, and capacity to be coated by polymers as core-shell nanoparticles make Fe 2 O 3 NPs such an ideal carrier for pH-responsive drug delivery platforms, moreover, there is a potential for the reduction of Fe 2 O 3 based nanocarriers for loading biomolecules ( Figure 2 ) [ 61 , 62 , 63 , 64 , 65 , 66 ]. These characteristics provide sufficient room for loading antitumor medications.…”

A mini review on green nanotechnology and its development in biological effects

“…Plant sections such as leaves, stems, roots, shoots, flowers, barks, seeds, and their metabolites have all been effectively utilized in the fabrication of nanoparticles (Abdelghany et al 2022 ; Al-Zahrani et al 2022a ; Aref and Salem 2020 ). Green synthesis of NPs using plants has more benefits than other approaches since it is a one-step procedure, economical, produces a large quantity of metabolites, is cost-effective, and ecologically sound (Ahn et al 2019 ).…”

“…A new and developing environmentally friendly science is the synthesis of nano-materials utilizing bacteria or plants. Many researchers have been synthesizing nano-materials using biological models (Soliman et al 2022a ; Al-Rajhi et al 2022 ; Al-Zahrani et al 2022a , b ). The use of science in nanotechnology to manipulate matter at the atomic level.…”

Green Synthesis of Iron Oxide (Hematite) Nanoparticles and Their Influence on Sorghum bicolor Growth under Drought Stress

“…These extracts contain secondary metabolites such as polysaccharides, polyphenolic compounds, amino acids, vitamins, and alkaloids, among other compounds that act as reducing, stabilizing, and capping agents [ 39 , 40 ]. In particular, iron oxide NPs have been synthesized from different plant species including Lagenaria Siceraria [ 17 ], Buddleja lindleyana extract [ 41 ], and Caesalpinia coriaria (Jacq.) [ 42 ], amongst others.…”