Green Synthesis of Capped Gold Nanoparticles and Their Effect On Gram-Positive and Gram-Negative Bacteria

Rao, Yashvant; Inwati, Gajendra Kumar; Singh, Man

doi:10.4155/fsoa-2017-0062

Cited by 48 publications

(24 citation statements)

References 38 publications

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“…The diffraction peaks of 38.1° relates to (111), 44.5° relates to (200), 64.7° relates to (220), and 77.8° relates to (311) facets of the face center cubic (FCC) crystal lattice; these agree with reported values for similar gold nanostructures [ 69 ]. The reported peak values also matched the planes and face-centered cubic structures of AuNPs prepared by other green syntheses methods [ 22 , 70 , 71 , 72 ].…”

Section: Resultssupporting

confidence: 78%

Synthesis of Gold Nanoparticles Using Leaf Extract of Ziziphus zizyphus and their Antimicrobial Activity

et al. 2018

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(1) Background: There is a growing need for the development of new methods for the synthesis of nanoparticles. The interest in such particles has raised concerns about the environmental safety of their production methods; (2) Objectives: The current methods of nanoparticle production are often expensive and employ chemicals that are potentially harmful to the environment, which calls for the development of “greener” protocols. Herein we describe the synthesis of gold nanoparticles (AuNPs) using plant extracts, which offers an alternative, efficient, inexpensive, and environmentally friendly method to produce well-defined geometries of nanoparticles; (3) Methods: The phytochemicals present in the aqueous leaf extract acted as an effective reducing agent. The generated AuNPs were characterized by Transmission electron microscopy (TEM), Scanning electron microscope (SEM), and Atomic Force microscopy (AFM), X-ray diffraction (XRD), UV-visible spectroscopy, energy dispersive X-ray (EDX), and thermogravimetric analyses (TGA); (4) Results and Conclusions: The prepared nanoparticles were found to be biocompatible and exhibited no antimicrobial or antifungal effect, deeming the particles safe for various applications in nanomedicine. TGA analysis revealed that biomolecules, which were present in the plant extract, capped the nanoparticles and acted as stabilizing agents.

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Section: Resultssupporting

confidence: 78%

Synthesis of Gold Nanoparticles Using Leaf Extract of Ziziphus zizyphus and their Antimicrobial Activity

et al. 2018

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“…The peak of diffraction observed at 77.8°, 64.7°, 44.5°and 38.1°r elated to the facets 311, 220, 200 and 111, respectively, of the face-centered cubic (FCC) crystal lattice, which are compatible with the recorded values of different gold nanostructures [27]. The recorded peak values have matched Au NP's FCC cubic structures as well as planes that were developed by other approaches of green synthesis [28][29][30][31]. Figure 4 shows the FTIR spectrum of the prepared AuNPs, which showed a strong absorption band at 3,400 cm −1 corresponding to O-H stretching vibrations of polyphenolic groups.…”

Section: Resultssupporting

confidence: 82%

A novel biofabrication of gold nanoparticles using Erythrina senegalensis leaf extract and their ameliorative effect on mycoplasmal pneumonia for treating lung infection in nursing care

Hong

2020

Green Processing and Synthesis

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This study showed the fabrication of gold nanoparticles (AuNPs) utilizing Erythrina senegalensis leaf extract as an effective, low-cost and eco-friendly approach. The bioconstituents existing in the E. senegalensis leaf extract are accountable for reducing and stabilization of NPs. The produced AuNPs were studied by using transmission electron microscopy, X-ray diffraction, UV-visible (UV-Vis) spectroscopy, Fourier transform infrared spectroscopy and energy-dispersive X-ray spectroscopy. In addition, this study also showed that the prepared AuNPs exhibited very good antipneumonial activity against mycoplasmal pneumonia in the investigational animals, indicating their potential for the development of new therapeutic drugs for the lung injury treatments in in the future.

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“…The synthesis of TM-AuNPs was further confirmed by UV–visible spectrophotometry analysis and this data was used to determine the optimum plant concentration to produce the TM-AuNPs from each of the six TM extracts. The Surface Plasmon Resonance (SPR) of AuNPs results in an absorption maxima (or λ max ) in the region of 500–600 nm [ 10 , 39 ] as is illustrated in Figure 2 , which shows the UV–visible spectra for TM-AuNPs produced with the six different TM extracts at 25 °C and 70 °C. These spectra also represent the AuNPs synthesized with the optimal plant extract concentrations.…”

Section: Resultsmentioning

confidence: 99%

Synthesis of Biogenic Gold Nanoparticles from Terminalia mantaly Extracts and the Evaluation of Their In Vitro Cytotoxic Effects in Cancer Cells

et al. 2020

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Scientists have demonstrated the potential of plant materials as ‘green’ reducing and stabilizing agents for the synthesis of gold nanoparticles (AuNPs) and opened new ecofriendly horizons to develop effective and less harmful treatment strategies. The current study demonstrated the use of Terminalia mantaly (TM) extracts to synthesize AuNPs with enhanced cytotoxic effects. The TM-AuNPs were synthesized at 25 and 70 °C using water (WTM) and methanolic (MTM) extracts of the leaf, root and stem/bark parts of the plant. The TM-AuNPs were characterized using UV–visible spectrophotometry, dynamic light scattering (DLS), transmission electron microscopy, energy dispersive X-ray (EDX), selection area electron diffraction (SAED) and Fourier transform infrared (FTIR) spectroscopy. Majority of the TM-AuNPs were spherical with a mean diameter between 22.5 and 43 nm and were also crystalline in nature. The cytotoxic effects of TM-AuNPs were investigated in cancer (Caco-2, MCF-7 and HepG2) and non-cancer (KMST-6) cell lines using the MTT assay. While the plant extracts showed some cytotoxicity towards the cancer cells, some of the TM-AuNPs were even more toxic to the cells. The IC50 values (concentrations of the AuNPs that inhibited 50% cell growth) as low as 0.18 µg/mL were found for TM-AuNPs synthesized using the root extract of the plant. Moreover, some of the TM-AuNPs demonstrated selective toxicity towards specific cancer cell types. The study demonstrates the potential of TM extracts to produce AuNPs and describe the optimal conditions for AuNPs using TM extracts. The toxicity of some the TM-AuNPs can possibly be explored in the future as an antitumor treatment.

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Green Synthesis of Capped Gold Nanoparticles and Their Effect On Gram-Positive and Gram-Negative Bacteria

Cited by 48 publications

References 38 publications

Synthesis of Gold Nanoparticles Using Leaf Extract of Ziziphus zizyphus and their Antimicrobial Activity

Synthesis of Gold Nanoparticles Using Leaf Extract of Ziziphus zizyphus and their Antimicrobial Activity

A novel biofabrication of gold nanoparticles using Erythrina senegalensis leaf extract and their ameliorative effect on mycoplasmal pneumonia for treating lung infection in nursing care

Synthesis of Biogenic Gold Nanoparticles from Terminalia mantaly Extracts and the Evaluation of Their In Vitro Cytotoxic Effects in Cancer Cells

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