Green synthesis of copper &amp; copper oxide nanoparticles using the extract of seedless dates

Mohamed, Elwy A.

doi:10.1016/j.heliyon.2019.e03123

Cited by 125 publications

(56 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The hybrid NPs of both metals shows the presence of different functional groups at 1604, 1387, 1221, 1028 and 768. These absorption bands show the presence of CH 3 , Phosphate II, glycogen and guanine [52]. These functional groups are due to C-O and C-C stretching and C-O-H deformation motions.…”

Section: Fourier Transform Infrared Spectrometer (Ftir)mentioning

confidence: 97%

Curcuma longa Mediated Synthesis of Copper Oxide, Nickel Oxide and Cu-Ni Bimetallic Hybrid Nanoparticles: Characterization and Evaluation for Antimicrobial, Anti-Parasitic and Cytotoxic Potentials

et al. 2021

View full text Add to dashboard Cite

Nanoparticles have long been known and their biomedical potent activities have proven that these can provide an alternative to other drugs. In the current study, copper oxide, nickel oxide and copper/nickel hybrid NPs were biosynthesized by using Curcuma longa root extracts as a reducing and capping agent, followed by characterization via UV-spectroscopy, Fourier transformed infrared spectroscopy (FTIR), energy dispersive X-ray (EDX), powder X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), thermo galvanometric analysis (TGA), and band gap. FTIR spectroscopy shows the availability of various functional groups and biomolecules such as carbohydrate, protein, polysaccharides, etc. The EDX peak confirmed that the elemental nickel and copper were present in large quantity in the analyzed sample. Scanning electron micrographs showed that the synthesized CuO-NPs and NiO-NPs were polyhedral uniform and homogeneous in morphology, while the copper/nickel hybrid NPs were well dispersed, spherical in shape, and uniform in size. TEM micrographs of CuO-NPs had 27.72 nm, NiO had 23.13 nm and, for their hybrid, the size was 17.38 nm, which was confirmed respectively. The CuO and NiO NPs possessed spherical- to multi-headed shapes, while their hybrid showed a complete spherical shape, small size, and polydispersed NPs. The XRD spectra revealed that the average particle size for CuO, NiO, and hybrid were 29.7 nm, 28 nm and 27 nm, respectively. Maximum anti-diabetic inhibition of (52.35 ± 0.76: CuO-NPs, 68.1 ± 0.93: NiO-NPs and 74.23 ± 0.42: Cu + Ni hybrids) for α-amylase and (39.25 ± 0.18 CuO-NPs, 52.35 ± 1.32: NiO-NPs and 62.32 ± 0.48: Cu + Ni hybrids) for α-glucosidase were calculated, respectively, at 400 µg/mL. The maximum antioxidants capacity was observed as 65.1 ± 0.83 μgAAE/mg for Cu-Ni hybrids, 58.39 ± 0.62 μgAAE/mg for NiO-NPs, and 52.2 ± 0.31 μgAAE/mg for CuO-NPs, respectively, at 400 μg/mL. The highest antibacterial activity of biosynthesized NPs was observed against P. aeuroginosa (28 ± 1.22) and P. vulgaris (25 ± 1.73) for Cu + Ni hybrids, respectively. Furthermore, the antibiotics were coated with NPs, and activity was noted. Significant anti-leishmanial activity of 60.5 ± 0.53 and 68.4 ± 0.59 for Cu + Ni hybrids; 53.2 ± 0.48 and 61.2 ± 0.44 for NiO-NPs; 49.1 ± 0.39 and 56.2 ± 0.45 for CuO-NPs at 400 μg/mL were recorded for promastigote and amastigotes, respectively. The biosynthesized NPs also showed significant anti-cancerous potential against HepG2 cell lines. It was concluded from the study that NPs are potential agents to be used as an alternative to antimicrobial agents.

show abstract

Section: Fourier Transform Infrared Spectrometer (Ftir)mentioning

confidence: 97%

Curcuma longa Mediated Synthesis of Copper Oxide, Nickel Oxide and Cu-Ni Bimetallic Hybrid Nanoparticles: Characterization and Evaluation for Antimicrobial, Anti-Parasitic and Cytotoxic Potentials

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Metabolites such as sugar, terpenoids, polyphenols, alkaloids, phenolic acids, and proteins play essential roles in the reduction of metal ions to nanoparticles and support the stability of nanoparticles [2,6]. Many works suggest that plant extracts such as Solanum Lycopersicum [7], Eclipta prostrate [3], Punica granatum [8], Plantago asiatica [9], Gnidia glauca and Plumbago zeylanica [10], Uncaria gambir Roxb [11], Camellia sinensis [12], Moringa oleifera [13], Crataegus pontica L [14], dates [15] and other plants have been explored for CuNPs synthesis. Different plants produce different nanoparticle characteristics.…”

Section: Introductionmentioning

confidence: 99%

Green synthesis and characterization of copper nanoparticles using Piper retrofractum Vahl extract as bioreductor and capping agent

Amaliyah

Pangesti

Masruri

et al. 2020

Heliyon

View full text Add to dashboard Cite

The copper nanoparticles (CuNPs) have attracted much attention due to their application in diverse fields. The applications of CuNPs depend on their physical and chemical properties. This study presents the first report for the use of medicinal fruit extract of Piper retrofractum Vahl as an eco-friendly reagent in the synthesis of CuNPs using copper sulfate as a starting material. Piper retrofractum Vahl extract was employed as a bioreductor as well as a capping agent in the formation of CuNPs. The reaction process was assisted by sonication and stirring. The influences of extract concentration, pH, temperature, and reaction time on the size of CuNPs were studied in detail. The morphology and structure of synthesized CuNPs were characterized by UV-Vis, FT-IR, SEM-EDS, TEM, and XRD. The UV-Vis measurement showed the surface plasmon resonance (SPR) peak at 234-255 nm, whereas FTIR characteristic peaks of metal-oxygen (Cu-O) were confirmed in the range 550-570 cm À1 and Cu-O-H bonds led to bending absorptions in the region 870-880 cm À1. The synthesized CuNPs possess the spherical shapes and high content of copper (70.3%) as confirmed by SEM-EDS. From the TEM micrograph, it can be seen that the particle size distribution of CuNPs has a high uniformity with a size of 2-10 nm under the optimum condition. The crystalline nature of CuNPs as confirmed by XRD showed the crystallinity phase of 26.4%. The synthesized CuNPs have relatively good stability and could inhibit Escherichia coli and Staphylococcus aureus. The results proved that Piper retrofractum Vahl fruit extract could be applied for a greener synthesis of CuNPs with high uniformity of particle sizes.

show abstract

“…UV visible spectroscopy and PCS study further confirm that the synthesised nanoparticles were in Cu° ionic state and possess monomodal size distribution with symmetric (spherical) morphology [ 35 ]. The magnitude of the zeta potential determines the extent of the electrostatic repulsion between the same species constituting the colloid, zeta potential is considered to be an important physical measure for the colloidal stability of nanoparticles [ 36 ]. Zeta potential of as‐synthesised CuNPs was determined from electrophoretic mobility measured by the phase angle light scattering (PALS).…”

Section: Resultsmentioning

confidence: 99%

Ecotoxicity of as‐synthesised copper nanoparticles on soil bacteria

Sharma

Goyal

Chudasama

2021

IET Nanobiotechnology

View full text Add to dashboard Cite

Release of metallic nanoparticles in soil poses a serious threat to the ecosystem as they can affect the soil properties and impose toxicity on soil microbes that are involved in the biogeochemical cycling. In this work, in vitro ecotoxicity of as-synthesised copper nanoparticles (CuNPs) on Bacillus subtilis (MTCC No. 441) and Pseudomonas fluorescens (MTCC No. 1749), which are commonly present in soil was investigated. Three sets of colloidal CuNPs with identical physical properties were synthesised by chemical reduction method with per batch yield of 0.2, 0.3 and 0.4 gm. Toxicity of CuNPs against these soil bacteria was investigated by MIC (minimum inhibitory concentration), MBC (minimum bactericidal concentration), cytoplasmic leakage and ROS (reactive oxygen species) assay. MIC of CuNPs were in the range of 35-60 µg/ml and 35-55 µg/ml for B. subtilis and P. fluorescens respectively, while their MBC ranged from 40-70 µg/ml and 40-60 µg/ml respectively. MIC and MBC tests reveal that Gram-negative P. fluorescens was more sensitive to CuNPs as compared to Gram positive B. subtilis mainly due to the differences in their cell wall structure and composition. CuNPs with smaller hydrodynamic size (11.34 nm) were highly toxic as revealed by MIC, MBC tests, cytoplasmic leakage and ROS assays, which may be due to the higher active surface area of CuNPs and greater membrane penetration. Leakage of cytoplasmic components and generation of extracellular oxidative stress by reactive oxygen species (ROS) causes cell death. The present study realizes in gauging the negative impact of inadvertent release of nanoparticles in the environment, however, in situ experiments to know its overall impact on soil health and soil microflora can help in finding solution to combat ecotoxicity of nanoparticles.This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

show abstract

Green synthesis of copper & copper oxide nanoparticles using the extract of seedless dates

Cited by 125 publications

References 32 publications

Curcuma longa Mediated Synthesis of Copper Oxide, Nickel Oxide and Cu-Ni Bimetallic Hybrid Nanoparticles: Characterization and Evaluation for Antimicrobial, Anti-Parasitic and Cytotoxic Potentials

Curcuma longa Mediated Synthesis of Copper Oxide, Nickel Oxide and Cu-Ni Bimetallic Hybrid Nanoparticles: Characterization and Evaluation for Antimicrobial, Anti-Parasitic and Cytotoxic Potentials

Green synthesis and characterization of copper nanoparticles using Piper retrofractum Vahl extract as bioreductor and capping agent

Ecotoxicity of as‐synthesised copper nanoparticles on soil bacteria

Contact Info

Product

Resources

About