Copper is an important metal in analytical and industrial fields as it has excellent thermal and electrical properties. In many disciplines, like electronics, optics, and others, copper nanoforms pay more attention than other noble metals nanoparticles. Attractive are its natural abundance, low costs and high activity toward many analytes with simultaneous physical stability. Extensive use has brought new types of sensors and practical implementations. The objective of this paper is to present crucial developments of copper material in the sensing field. Practical applications in the environmental section, like chemical oxygen demand measurement or carbon dioxide reduction reaction for atmospheric CO2 reduction; technological sensors like organic light-emitting devices, electronic tongue for alcohol type determination, human skin touch and move sensor; and medical sensors for glucose, alcohol, dopamine or paracetamol detection were presented.