Green synthesis of gold nanoparticles (Au NPs) using Tribulus terrestris extract: Investigation of its catalytic activity in the oxidation of sulfides to sulfoxides and study of its anti-acute leukemia activity

Zhao, Peng; El‐kott, Attalla F.; Ahmed, Ahmed Ezzat; Khames, Ahmed; Zein, Mohamed A.-E.

doi:10.1016/j.inoche.2021.108781

Cited by 40 publications

(5 citation statements)

References 88 publications

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“…The face-centered cubic (FCC) crystalline structure of Zi -AuNPs was confirmed via XRD analysis that is displayed in Figure a as this analysis is reckoned as an essential step in determining the crystal structure of nanomaterials. , Four distinguishing peaks of Au were observed at 37.31, 44.31, 64.51, and 78.73° matching the planes of (111), (200), (220), and (311), respectively. Moreover, the main growth orientation was the (111) plane as previously reported in different works . These values were matching the reported standards JCPDS file no.…”

Section: Resultssupporting

confidence: 89%

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Facile Synthesis of Gold Nanoparticles for Anticancer, Antioxidant Applications, and Photocatalytic Degradation of Toxic Organic Pollutants

et al. 2022

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In the current study, a facile, rapid, and ecologically safe photosynthesis of gold nanoparticles (AuNPs) that remained stable for 3 months is reported to advocate the main aspects of green chemistry, such as safer solvents and auxiliaries, and the use of renewable feedstock. Zi-AuNPs were phytosynthesized by the aqueous extract of Ziziphus spina-christi leaves, and numerous techniques were employed for their characterization. The results demonstrated the successful phytofabrication of crystalline AuNPs with brownish-black color, spherical nanoparticles with a size between 0 and 10 nm, a plasmon peak at 540 nm, and a surface charge of −25.7 mV. Zi-AuNPs showed an effective photodegradation efficiency (81.14%) against malachite green and a good recycling capacity of 69.2% after five cycles of regeneration. The cytotoxicity test by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay signified a high anticancer efficiency for both Zi-AuNPs and Z. spina-christi extract against human breast cancer cells (MCF7 cell line) with IC50’s of 48 and 40.25 μg/mL, respectively. Highly efficient antioxidant capabilities were proven with 2,2-diphenyl-1-picrylhydrazyl (DPPH) removal percentages of 67.5% for Zi-AuNPs and 92.34% for Z. spina-christi extract.

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Section: Resultssupporting

confidence: 89%

“…Moreover, the main growth orientation was the (111) plane as previously reported in different works. 35 These values were matching the reported standards JCPDS file no. 04-0784 for crystalline Au.…”

Section: High-resolution Transmissionsupporting

confidence: 77%

Facile Synthesis of Gold Nanoparticles for Anticancer, Antioxidant Applications, and Photocatalytic Degradation of Toxic Organic Pollutants

et al. 2022

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“…The 50% inhibition of cancer cells was achieved at 468 µg/mL. In addition, staining assays were conducted, and necrosis was observed as a cause of cell death [ 184 ].…”

Section: Green Synthesis Of Aunps For Cancer Theranosticsmentioning

confidence: 99%

Application of Green Gold Nanoparticles in Cancer Therapy and Diagnosis

et al. 2022

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Nanoparticles are currently used for cancer theranostics in the clinical field. Among nanoparticles, gold nanoparticles (AuNPs) attract much attention due to their usability and high performance in imaging techniques. The wide availability of biological precursors used in plant-based synthesized AuNPs allows for the development of large-scale production in a greener manner. Conventional cancer therapies, such as surgery and chemotherapy, have significant limitations and frequently fail to produce satisfying results. AuNPs have a prolonged circulation time, allow easy modification with ligands detected via cancer cell surface receptors, and increase uptake through receptor-mediated endocytosis. To exploit these unique features, studies have been carried out on the use of AuNPs as contrast agents for X-ray-based imaging techniques (i.e., computed tomography). As nanocarriers, AuNPs synthesized by nontoxic and biocompatible plants to deliver therapeutic biomolecules could be a significant stride forward in the effective treatment of various cancers. Fluorescent-plant-based markers, including AuNPs, fabricated using Medicago sativa, Olax Scandens, H. ambavilla, and H. lanceolatum, have been used in detecting cancers. Moreover, green synthesized AuNPs using various extracts have been applied for the treatment of different types of solid tumors. However, the cytotoxicity of AuNPs primarily depends on their size, surface reactivity, and surface area. In this review, the benefits of plant-based materials in cancer therapy are firstly explained. Then, considering the valuable position of AuNPs in medicine, the application of AuNPs in cancer therapy and detection is highlighted with an emphasis on limitations faced by the application of such NPs in drug delivery platforms.

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“…113 In view of the environmental impact, eco-friendly green synthesis methods have currently become popular. [114][115][116][117][118][119][120] Current strategies of ''green'' concern include the use of nontoxic chemicals, biodegradable polymers, and environmentally benign solvents. 121 In the green synthesis methods, the extracts from living organisms such as leaves, stems, roots, seeds, owers, fruit, whole plant, fungi, and algae are available as reducing and capping agents.…”

Section: Synthesis Of Au Npsmentioning

confidence: 99%

Gold nanocrystals: optical properties, fine-tuning of the shape, and biomedical applications

Wei

Yang

et al. 2022

RSC Adv.

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Green synthesis of gold nanoparticles (Au NPs) using Tribulus terrestris extract: Investigation of its catalytic activity in the oxidation of sulfides to sulfoxides and study of its anti-acute leukemia activity

Cited by 40 publications

References 88 publications

Facile Synthesis of Gold Nanoparticles for Anticancer, Antioxidant Applications, and Photocatalytic Degradation of Toxic Organic Pollutants

Facile Synthesis of Gold Nanoparticles for Anticancer, Antioxidant Applications, and Photocatalytic Degradation of Toxic Organic Pollutants

Application of Green Gold Nanoparticles in Cancer Therapy and Diagnosis

Gold nanocrystals: optical properties, fine-tuning of the shape, and biomedical applications

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