Green synthesis of gold nanoparticles using Cinnamomum zeylanicum leaf broth

Smitha, S.L.; Philip, Daizy; Gopchandran, K.G.

doi:10.1016/j.saa.2009.08.007

Cited by 341 publications

(136 citation statements)

References 38 publications

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“…A significant variation was also observed in the rate of synthesis with variation in the concentration of the chloroauric acid. TEM micrographs showed that GGLE and GGSE could synthesize AuNPs of exotic shapes like nanotriangles, hexagons and spheres which is well in agreement with the previous reports [21,22,25,45].…”

Section: Discussionsupporting

confidence: 92%

“…Recently we have reported the synthesis of gold nanoparticles using tuber extract of D. bulbifera, a potent medicinal plant [22]. Similarly, recently synthesis of AuNPs have been reported employing leaf extract of medicinal plants such as, Azadirachta indica, Cinnamomum camphora, Cinnamomum zeylanicum, Eucalyptus camaldulensis and Murraya koenigii [23][24][25][26][27]. However, there are no reports on the potential of leaf and stem extracts of Gnidia glauca for synthesis of AuNPs.…”

Section: Introductionmentioning

confidence: 99%

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Gnidia glauca Leaf and Stem Extract Mediated Synthesis of Gold Nanocatalysts with Free Radical Scavenging Potential

Ghosh¹,

Patil²,

Chopade³

et al. 2016

J Nanomed Nanotechnol

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Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Gnidia glauca Leaf and Stem Extract Mediated Synthesis of Gold Nanocatalysts with Free Radical Scavenging Potential

Ghosh¹,

Patil²,

Chopade³

et al. 2016

J Nanomed Nanotechnol

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“…In recent years, synthesis of nanoparticles by using plants is gaining importance due to its effortlessness and eco-friendless [11]- [13]. Recently the biological synthesis of gold nanoparticles using many spices such as black seed (Nigella sativa), garlic, curcumin, Cinnamomum zeylanicum and clove (Syzygium aromaticum) has been reported [14]- [23]. The development of green metallic nanoparticles in present research is associated with field of applied microbiology, industrial and medicinal field [12] [13].…”

Section: Introductionmentioning

confidence: 87%

Green Synthesis and Characterization of Gold Nanoparticles: Study of Its Biological Mechanism in Human SUDHL-4 Cell Line

Parida¹,

Biswal²,

Bindhani³

2014

ABC

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In this investigation, the anticancer potentiality and biological mechanism of gold nanoparticles (AuNPs) was studied in SUDHL-4 cell line. Metallic AuNPs were prepared and stabilized with ethanol clove (Syzygium aromaticum) extract. The green synthesis of AuNPs was characterized and evaluated by UV-Visible Spectroscopic, X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Transmission electron microscopy (TEM), Dynamic Light Scattering (DLS) and biological activities using various biochemical assays. Green synthesis of AuNPs was confirmed by instrument method. The TEM images show polydisperse, mostly spherical AuNPs particles of 12 -20 nm. AuNPs were decreased the growth and viability of SU-DHL-4 cell line and increased the apoptosis. The treatments of SU-DHL-4 cells with AuNPs resulted in a moderate considerably increase in Reactive oxygen species (ROS) production. We measured apoptosis by Annexin-V/propidium iodide (PI) in the existence and nonexistence of the antioxidant N-acetyl-Lcysteine (NAC), the glutathione-depleting agent buthionine sulfoximine (BSO), or caspase inhibitors to determine the mechanism of cell death. AuNPs are unique potential anticancer agents that cause ROS-dependent apoptosis in SUDHL-4 cell line which was improved by depletion of glutathione (GHS) and inhibited by N-acetyl-L-cysteine on Z-VAD-FMK.

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“…[ 10] Initially, there was no significant peak at 2 min, but after 5 min, the building of peak at 540 nm marked the initiation of synthesis of AuNPs. The subsequent rise in the peak with a maximum at 20 min supported that the reported route of AuNPs synthesis is novel as well as rapid as compared to M. jalapa flower wherein the synthesis was reported to be completed in 2 h. [11] The rapidity in biosynthesis of AuNPs than other biosynthetic methods is attributed to strong antioxidant capacity of this plant.…”

Section: Biosynthesis Of Aunpsmentioning

confidence: 99%

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Anita

2017

AJP

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Aim: The aim of this study is to synthesize gold nanoparticles (AuNPs) from flower extract of Alhagi maurorum and aqueous gold chloride through a simple green route. Materials and Methods: AuNPs were synthesized by the reaction mixture containing freshly prepared flower aqueous extract and HAuCl 4 solution. The reduction of Au 3+ ions to AuNPs was monitored at different time intervals (0-180 min), at different concentration of chloroauric acid (0.1-2.0 mM), and at varying content of flower extract (1.0-25.0 ml). Characterization and storage stability of synthesized AuNPs were also noticed in this study. Results and Discussion: Optimization studies showed that 0.5 mM of chloroauric acid and lower amount (5.0 ml) of flower extract in 1:5 ratio facilitated maximum synthesis of AuNPs at an incubation period of 20 min. Transmission electron microscopic study revealed a size range of 12-24 nm and crystalline nature of biosynthesized AuNPs. The possible involvement of biomolecules in the formation of AuNPs was confirmed by Fourier transform infrared spectroscopy (FTIR) study. Stability of synthesized AuNPs showed only some microaggregates in the reaction mixture after 120 days which indicates the formation of highly stable AuNPs by a novel, simple, non-toxic, and eco-friendly route. Conclusions: Flower extract of A. maurorum could be used as an efficient green material for the rapid and consistent synthesis of AuNPs and their use as an antimicrobial agent in drug delivery system and in pharmaceutical and medical industry for the human welfare.

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Green synthesis of gold nanoparticles using Cinnamomum zeylanicum leaf broth

Cited by 341 publications

References 38 publications

Gnidia glauca Leaf and Stem Extract Mediated Synthesis of Gold Nanocatalysts with Free Radical Scavenging Potential

Gnidia glauca Leaf and Stem Extract Mediated Synthesis of Gold Nanocatalysts with Free Radical Scavenging Potential

Green Synthesis and Characterization of Gold Nanoparticles: Study of Its Biological Mechanism in Human SUDHL-4 Cell Line

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