Green Synthesis of Hydroxyapatite Nanoparticles from Wrightia tinctoria and Its Antibacterial Activity

Ragunath, C; Kousalya, L; Ramasubramanian, V.; Anitha, S

doi:10.1007/s12668-022-01012-x

Cited by 7 publications

(2 citation statements)

References 20 publications

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“…The results seen in Figure 4 showed Subsequently, the crystallinity of the as-synthesized HAp was studied with X-ray diffraction (XRD). Figure 3d shows the presence of reflections peaks at certain 2θ angles, where they can be ascribed as follows: 22.59 [55][56][57][58]. The reflection peaks were also identified based on the Crystallography Open Database (COD)-in particular, the 96-901-1092 card.…”

Section: Turbiscan Analysismentioning

confidence: 99%

Nanohydroxyapatite Loaded with 5-Fluorouracil and Calendula officinalis L. Plant Extract Rich in Myo-Inositols for Treatment of Ovarian Cancer Cells

Osial,

Wilczewski,

Szulc

et al. 2023

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In this study, the hydroxyapatite (HAp) in the form of nanoparticles was synthesized through the wet co-precipitation method and loaded with plant extract from Calendula officinalis L. rich in biologically active myo-inositol, and the 5-fluorouracil anticancer drug. The obtained nanomaterials have rod-like structures approx. 30 nm in diameter and 100 nm in length. FT-IR analysis results proved the immobilization of biologically active compounds. The loading of plant extract into the carrier improved the stability of colloidal suspension, which was confirmed with turbidimetry. The composite modified with calendula extract and drug (HAp@Cal@5-flu) effectively scavenges the DPPH radicals, with a radical scavenging activity (RSA) of about 20.0 ± 1.3%. The effect is supported by the DFT calculations of the HOMO-LUMO, presenting the chemical reactivity of the molecules loaded into the HAp. The in vitro cytotoxicity results on SKOV-3 ovarian cancer cells show the pronounced cytotoxic effect of the HAp@Cal@5-flu. The calendula extract loading into the carrier provided better interactions with the tumorous biomimetic membranes studied with a Langmuir trough, making it a promising material in nano-biomedicine, including drug delivery and targeted cancer treatment.

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Section: Turbiscan Analysismentioning

confidence: 99%

Nanohydroxyapatite Loaded with 5-Fluorouracil and Calendula officinalis L. Plant Extract Rich in Myo-Inositols for Treatment of Ovarian Cancer Cells

Osial,

Wilczewski,

Szulc

et al. 2023

Coatings

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“…Agglomeration usually causes a reduction in surface energy and is a favored phenomenon. Te creation of core-shell type surface-functionalized HAp NPs has attracted a lot of attention since the polymer shell inhibits the agglomeration NPs and increases their stability [17][18][19][20]. Te usage of bioextracts as a polymer matrix improves the efcient function of nanoparticles and environmental safety.…”

Section: Introductionmentioning

confidence: 99%

Green Synthesis of Hydroxyapatite Nanoparticles Using Monoon longifolium Leaf Extract for Removal of Fluoride from Aqueous Solution

Ganta

Hirpaye

Sabu

et al. 2022

Journal of Chemistry

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Hydroxyapatite (Ca10(PO4)6(OH)2) calcium phosphate is a robust and viable magnetic material for the treatment of polluted air, water, and soil. Because of its unique structure and appealing properties such as high adsorption capabilities, acid-base adaptability, ion-exchange capability, and thermal stability, hydroxyapatite (HAp) has a lot of potential in the field of environmental management. An aqueous extract of Monoon longifolium leaves was used for the preparation of hydroxyapatite nonparticles as the adsorbent for fluoride ion removal from aqueous solution in this work, resulting in bio-based hydroxyapatite nanoparticles. The prepared adsorbent was characterized by using instrumental techniques such as TGA/DTA, XRD, AAS, FT-IR, and UV-Vis spectroscopy as well as SEM. The batch adsorption approach was used to determine the optimum adsorption efficiency of HAp NPs under various experimental conditions. As a result, the best removal efficiency corresponds to 0.75 g HAp NPs, 15 mg/L, and pH 7 at 50 minutes (96%). The equilibrium adsorption data were better fitted into the Freundlich isotherms (R2 = 0.99), and the pseudo-second-order kinetic model was found to be suitable (R2 = 0.99) for the kinetic model. Fluoride ion adsorption on HAp NPs is spontaneous, endothermic, and possible at temperatures over 318 K, according to thermodynamic calculations. The results hint at a conclusion that the synthesized HAp NPs were an efficient adsorbent for the removal of fluoride ions and the overall process can be an economical choice for scaled-up water treatment processes.

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Green Synthesis of Hydroxyapatite Nanoparticles Using Semecarpus anacardium Linn leaf Extract: Examination of Anticancer Activity and its Apoptosis Induction

Rekha,

Ojha,

Mewada

et al. 2024

J Inorg Organomet Polym

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Green Synthesis of Hydroxyapatite Nanoparticles from Wrightia tinctoria and Its Antibacterial Activity

Cited by 7 publications

References 20 publications

Nanohydroxyapatite Loaded with 5-Fluorouracil and Calendula officinalis L. Plant Extract Rich in Myo-Inositols for Treatment of Ovarian Cancer Cells

Nanohydroxyapatite Loaded with 5-Fluorouracil and Calendula officinalis L. Plant Extract Rich in Myo-Inositols for Treatment of Ovarian Cancer Cells

Green Synthesis of Hydroxyapatite Nanoparticles Using Monoon longifolium Leaf Extract for Removal of Fluoride from Aqueous Solution

Green Synthesis of Hydroxyapatite Nanoparticles Using Semecarpus anacardium Linn leaf Extract: Examination of Anticancer Activity and its Apoptosis Induction

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